| | 30918-54-8 Basic information More.. |
| Product Name: | Polyinosinic acid | | Synonyms: | POLY RL POTASSIUM SALT;POLYINOSINIC ACID POT. SALT, LYOPH., MR ~1200000;5'-Inosinic acid polymers;Polyinosinic acid;Polyinosinic acid (Poly I);5’-Inosinicacid,homopolymer;Poly(5’-inosinicacid);Poly(IMP) | | CAS: | 30918-54-8 | | MF: | C10H13N4O8P | | MW: | 348.21 | | EINECS: | 1592732-453-0 | | Mol File: | 30918-54-8.mol |  |
Use
Polyinosinic acid (Poly(I)) is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I).Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. (Poly(I).Poly(C)) is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
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30918-54-8
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