| | 6890-08-0 Basic information More.. |
| Product Name: | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE | | Synonyms: | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE;2-HYDROXY-1,3(2H,4H)-ISOQUINOLINEDIONE;2-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1,3-dione;1,3(2H,4H)-Isoquinolinedione, 2-hydroxy-;2-hydroxy-4h-isoquinoline-1,3-dione | | CAS: | 6890-08-0 | | MF: | C9H7NO3 | | MW: | 177.16 | | EINECS: | | | Mol File: | 6890-08-0.mol |  |
Use
2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. It was investigated its interaction with Mg2+ and Mn2+ using different spectroscopic techniques and report that 2-hydroxyisoquinoline-1,3(2H,4H)-dione forms a 1:1 complex with Mg2+ but a 1:2 complex with Mn2+. Antiviral agent.
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6890-08-0
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