| | 97519-39-6 Basic information More.. |
| Product Name: | Ceftibuten | | Synonyms: | (6r-(6-alpha,7-beta(z)))-yl)-4-carboxy-1-oxo-2-butenyl)amino)-8-oxo;[6R-[(6α，7β(Z)]]-7-[[2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-butenyl]amino]-8-oxo-5-thia-1-azabi-cyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cedax：Isocef;(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate;(6R,7R)-7-[[(Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-2-butenoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid;(6R,7R)-7α-[[(Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-butenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;antibiotic7432s;cephalosporin7432-s | | CAS: | 97519-39-6 | | MF: | C15H14N4O6S2 | | MW: | 410.42 | | EINECS: | 810-182-0 | | Mol File: | 97519-39-6.mol |  |
Use
Ceftibuten (Cedax) is a recently introduced, chemicallynovel analog of the oximino cephalosporins in which anolefinic methylene group (C＝CHCH2-) with Z stereochemistryhas replaced the syn oximino (CBNO-) group.This isosteric replacement yields a compound that retainsresistance to hydrolysis catalyzed by many β-lactamases,has enhanced chemical stability, and is orally active. Oralabsorption is rapid and nearly complete. It has the highestoral bioavailability of the third-generation cephalosporins.Ceftibuten is excreted largely unchanged in the urine andhas a half-life of about 2.5 hours. Plasma protein binding ofthis cephalosporin is estimated to be 63%.Ceftibuten possesses excellent potency against mostmembers of the Enterobacteriaceae family, H. influenzae,Neisseria spp., and M. catarrhalis. It is not active against S.aureus or P. aeruginosa and exhibits modest antistreptococcal activity. Ceftibuten is recommended in the managementof community-acquired respiratory tract, urinary tract, andgynecological infections.
- Ceftibuten
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- US $0.00-0.00 / mg
- 2024-04-10
- CAS:97519-39-6
- Min. Order: 10mg
- Purity: 90%+
- Supply Ability: 10g
- Ceftibuten
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- US $0.00 / Kg/Bag
- 2021-11-04
- CAS:97519-39-6
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 500kg
- Ceftibuten USP/EP/BP
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- US $1.10 / g
- 2021-07-01
- CAS:97519-39-6
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
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97519-39-6
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