| | 32450-26-3 Basic information More.. |
| Product Name: | COCHLIOQUINONE B | | Synonyms: | COCHLIOQUINONE B;20-De(acetyloxy)-11-deoxy-20-oxocochlioquinone A;Pyrano[3,2-a]xanthene-8,11-dione, 9-[(1S,3S)-1,3-dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-, (3R,4aR,6aR,12aR,12bR)- | | CAS: | 32450-26-3 | | MF: | C28H40O6 | | MW: | 472.61 | | EINECS: | | | Mol File: | 32450-26-3.mol |  |
Use
Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH-ubiquinone reductase inhibitor and phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have recently been shown to be antagonists of the human chemokine receptor, CCR5, in HIV-1.
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32450-26-3
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