| | 89786-04-9 Basic information More.. |
| Product Name: | Tazobactam acid | | Synonyms: | 4,4-dioxide,(2s-(2-alpha,3-beta,5-alpha))--triazol-1-ylmethyl);cl298741;ytr83oh;tazobactam acid;TAZOBACTAN ACID;(2S,3S,5R)-3-METHYL-4,4,7-TRIOXO-3-[1,2,3]TRIAZOL-1-YLMETHYL-4LAMBDA6-THIA-1-AZA-BICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID;Tazobactam, Free acid;2b-[(1,2,3-triazol-1-yl)methyl]-2a-methylpenam-3a-carboxylic acid 1,1-dioxide | | CAS: | 89786-04-9 | | MF: | C10H12N4O5S | | MW: | 300.29 | | EINECS: | 618-303-7 | | Mol File: | 89786-04-9.mol |  |
Use
Tazobactam is a penicillanic acid sulfone that is similar instructure to sulbactam. It is a more potent β-lactamaseinhibitor than sulbactam and has a slightly broader spectrumof activity than clavulanic acid. It has very weak antibacterialactivity. Tazobactam is available in fixed-dose, injectablecombinations with piperacillin, a broad-spectrum penicillinconsisting of an 8:1 ratio of piperacillin sodium to tazobactamsodium by weight and marketed under the trade name Zosyn.The pharmacokinetics of the two drugs are very similar. Bothhave short half-lives (t1/2 ～1 hour), are minimally proteinbound, experience very little metabolism, and are excreted inactive forms in the urine in high concentrations.Approved indications for the piperacillin–tazobactamcombination include the treatment of appendicitis, postpartumendometritis, and pelvic inflammatory disease caused byβ-lactamase–producing E. coli and Bacteroides spp., skin andskin structure infections caused by β-lactamase–producingS. aureus, and pneumonia caused by β-lactamase–producingstrains of H. influenzae.
- Tazobactam
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- US $0.00-0.00 / mg
- 2024-04-10
- CAS:89786-04-9
- Min. Order: 10mg
- Purity: 90%+
- Supply Ability: 10g
- Tazobactam
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- US $0.00 / kg
- 2024-02-27
- CAS:89786-04-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100 tons
- Tazobactam acid
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- US $90.00 / KG
- 2023-12-04
- CAS:89786-04-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 9000kg/per week
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89786-04-9
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