136434-34-9 Basic information More..
Product Name:Duloxetine hydrochloride
Synonyms:LY-248686 HCl;(γS)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride (1:1);(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride;LY-248686 hydrochloride;Duloxetine for system suitability;Duloxetine hydrochloride solution;(S)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine hydrochloride;Methanol( Test Duloxetine HCl, 1.0 mg/mL as free base)
CAS:136434-34-9
MF:C18H20ClNOS
MW:333.88
EINECS:603-962-5
Mol File:136434-34-9.mol
136434-34-9

Use

Duloxetine Hydrochloride acts as an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate. Duloxetine hydrochloride is a new kind of selective dual inhibitor of 5 hydroxy trptamine (5-ht) and norepinephrine reuptake, and thus having antidepressant effect, while also having inhibitory effect on the central pain. its pharmacological characteristic is being able to inhibit neuronal pre-synaptic membrane’s reuptake on 5-hydroxy trptamine and norepinephrine but instead have a low inhibitory effect on the reuptake of dopamine.

Duloxetine hydrochloride manufacturers

  • Duloxetine hydrochloride
  • US $3.00-1.00 / kg
  • 2024-03-15
  • CAS:136434-34-9
  • Min. Order: 1kg
  • Purity: 99.9%
  • Supply Ability: 10 tons
  • Duloxetine hydrochloride
  • US $45.00-35.00 / kg
  • 2024-01-16
  • CAS:136434-34-9
  • Min. Order: 1kg
  • Purity: 99.8%
  • Supply Ability: 200tons/year
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