| | 161973-10-0 Basic information More.. |
| Product Name: | Esomeprazole magnesium | | Synonyms: | MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, (T-4)-;ESOMEPRAZOLE MAGNESIUM/SODIUM;(T-4)-bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-magnesium;5-Methoxy-2-((S)-((4-Methoxy-3,5-diMethyl-2-pyridyl)Methyl)sulfinyl-1H-benziMidazole MagnesiuM salt;ESOMEPRAZOLE MAGNESIUM SAMPLE;Esomeprazole magnesium;Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide;Bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) magnesium | | CAS: | 161973-10-0 | | MF: | C34H36MgN6O6S2 | | MW: | 713.12 | | EINECS: | 627-029-7 | | Mol File: | 161973-10-0.mol |  |
Use
Esomeprazole magnesium,S-bis(5-rnethoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-l-yl) magnesiumtrihydrate (Nexium), is the S-enantiomer ofomeprazole. The benzimidazole PPIs contain a chiral sulfuratom that form an enantiomeric pair that is stable andinsoluble under standard conditions. The S-isomer ofomeprazole has slightly greater PPI activity, and its intrinsicclearance is approximately three times lower thanthat of R-omeprazole (15 vs. 43μL/min). The lowerclearance of S-omeprazole is related to slower metabolicclearance by the CYP2C19 isozyme. Although Romeprazoleis primarily transformed to the 5-hydroxymetabolite, the S-isomer is metabolized by O-demethylationand sulfoxidation, which contribute little to intrinsicclearance.
- Esomeprazole Magnesium
-
- US $150.00 / kg
- 2025-05-07
- CAS:161973-10-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 500kg
- Esomeprazole Magnesium
-
- US $90.00-62.00 / mg
- 2025-04-27
- CAS:161973-10-0
- Min. Order:
- Purity: 98.84%
- Supply Ability: 10g
- esomeprazole magnesium
-
- US $1.00 / KG
- 2025-03-21
- CAS:161973-10-0
- Min. Order: 1KG
- Purity: 99.99%
- Supply Ability: 200
|
|
161973-10-0
Recommend Suppliers |
|