| | 75438-57-2 Basic information More.. |
| Product Name: | Moxonidine | | Synonyms: | MOXONIDINE;MOXONIDINE HCL;4-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamin;bdf5895;be5895;BDF-5895 HCL;4-CHLORO-6-METHOXY-2-METHYL-5-(2-IMIDAZOLIN-2-YL)AMINOPYRIMIDINE HCL;4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMINE HYDROCHLORIDE | | CAS: | 75438-57-2 | | MF: | C9H12ClN5O | | MW: | 241.68 | | EINECS: | 629-833-3 | | Mol File: | 75438-57-2.mol |  |
Use
Moxonidine, also known as Physiotens, is a highly selective imidazoline receptor agonist-Ⅰ by excitement ventrolateral medulla nucleus (RVLM)-Ⅰ type imidazoline receptor in the peripheral sympathetic nerve activity decreased. This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata.
Moxonidine therefore causes a decrease in sympathetic nervous system activity and, therefore, a decrease in blood pressure.
It is a new type of antihypertensive drug, commonly used in the treatment of essential hypertension. Compared to the older central-acting antihypertensives, moxonidine binds with much greater affinity to the imidazoline I1-receptor than to the 2-receptor. In contrast, clonidine binds to both receptors with equal affinity.
It may have a role when thiazides, beta-blockers, ACE inhibitors and calcium channel blockers are not appropriate or have failed to control blood pressure.
- Moxonidine
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- US $0.00 / Kg/Bag
- 2025-05-07
- CAS:75438-57-2
- Min. Order: 50g
- Purity: 97.5%-102%
- Supply Ability: 1000g
- Moxonidine
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- US $107.00-47.00 / mg
- 2025-05-01
- CAS:75438-57-2
- Min. Order:
- Purity: ≥98%
- Supply Ability: 10g
- Moxonidine
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- US $107.00-47.00 / mg
- 2025-04-30
- CAS:75438-57-2
- Min. Order:
- Purity: ≥98%
- Supply Ability: 10g
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75438-57-2
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