| | 465-21-4 Basic information More.. |
| Product Name: | Bufalin | | Synonyms: | 22-dienolide,3,14-dihydroxy-,(3-beta,5-beta)-bufa-2;Bufalin, >=98%;22-dienolide,3-beta,14-dihydroxy-5-beta-bufa-2;BUFA-20,22-DIENOLIDE, 3,14-DIHYDROXY-, (3B,5B)-;(3BETA,5BETA)-3,14-DIHYDROXYBUFA-20,22-DIENOLIDE;3-BETA-14-DIHYDROXY-5-BETA-BUFA-20,22-DIENOLIDE;3BETA,14-DIHYDROXY-5BETA,20[22]-BUFADIENOLIDE;5BETA,20[22]-BUFADIENOLIDE-3BETA,14-DIOL | | CAS: | 465-21-4 | | MF: | C24H34O4 | | MW: | 386.52 | | EINECS: | | | Mol File: | 465-21-4.mol |  |
Use
Bufalin is one of the main components of dried secretions of toad which is Bufo , Bufalin has a strong surface anesthetic effect, and it has a long-lasting effect in rabbit cornea and human tongue tests which is stronger than cocaine, about 90 times of cocaine. intravenous fluid Toad (0.05mg/kg) on Anesthetized rabbits , anesthetized rabbits can be caused breathing excitement, cat can also be caused breathe excitement . Its effect is stronger than nikethamide , pentylenetetrazol, lobeline, etc. and it can antagonize morphine respiratory depression. Respiratory stimulant order: Bufalin>Resibufogenin= Cinobufagin =cinobufotaline> Japanese toad toxins.
Bufalin low concentrations (10-4) promote release of presynaptic acetylcholine on rat diaphragm , while high concentrations promote first then inhibit, and partly antagonize the neuromuscular blocking effects of Mg2 +,but no inhibition on choline esterase.
The above information is edited by the Chemicalbook of Tian Ye.
- Bufalin
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- US $0.00 / mg
- 2023-02-24
- CAS:465-21-4
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- Bufalin
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- US $15.00-10.00 / KG
- 2021-07-02
- CAS:465-21-4
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Bufalin
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- US $3.00 / KG
- 2020-01-19
- CAS:465-21-4
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1kg,5kg,50kg
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465-21-4
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