| 1127442-82-3 Basic information More.. |
Product Name: | IWR-1-endo | Synonyms: | [(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide;Benzamide, 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel-;endo-IWR 1;IWR-1-endo;rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide;rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide IWR-1-endo;IWR-1-endo, >=98%;ENDO-IWR 1;IWR-1-ENDO;IWR1;IWR 1 | CAS: | 1127442-82-3 | MF: | C25H19N3O3 | MW: | 409.44 | EINECS: | | Mol File: | 1127442-82-3.mol | |
Use
IWR-1-endo act as inhibitors of Wnt response. It appear that IWR compounds induce stabilization of Axin proteins via a direct interaction, which is a part of the b-catenin destruction complex (consists of Apc, Axin, Ck1 and Gsk3b). Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosi s.
- IWR-1-endo
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- US $1.00 / KG
- 2019-12-20
- CAS:1127442-82-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kgs
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1127442-82-3
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Company Name: |
Hubei Jusheng Technology Co.,Ltd.
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18871490254 |
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027-59599243 |
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Products Intro: |
Product Name:[(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide CAS:1127442-82-3 Purity:0.99 Package:5KG;1KG |
CB Index: |
58 |
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www.hubeijusheng.com |
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