| | 610798-31-7 Basic information More.. |
| Product Name: | Icotinib | | Synonyms: | BPI-2009;BP-1096;BPI-2009H;Lcotinib;Icotinib;[1,4,7,10]Tetraoxacyclododecino[2,3-g]quinazolin-4-amine, N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-;Icotinib int. N-1;N-(3-Ethynylphenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin | | CAS: | 610798-31-7 | | MF: | C22H21N3O4 | | MW: | 391.42 | | EINECS: | 1592732-453-0 | | Mol File: | 610798-31-7.mol |  |
Use
Icotinib (Conmana?, BetaPharma), an EGFR inhibitor, was approved by the China State FDA in 2011 for the treatment of NSCLC. Icotinib resembles erlotinib in possessing the N-(3-ethylnylphenyl) quinazolin-4-amine core scaffold of erlotinib that binds to the EGFR ATP pocket. An adjacent hydrophobic group was also retained while the solvent exposed two 2-methoxyethyoxysubstituents at the 6- and 7-positions of the quinazoline core were cyclized to afford the tetraoxacyclododecene moiety of icotinib. Efficacy and safety of icotinib as first-line therapy in patients has been evaluated for advanced NSCLC in recent clinical studies.
- Icotinib
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- US $15.00-10.00 / KG
- 2021-07-13
- CAS:610798-31-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Icotinib
-
- US $15.00-10.00 / KG
- 2021-07-10
- CAS:610798-31-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Icotinib
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- US $1.00 / KG
- 2019-07-06
- CAS:610798-31-7
- Min. Order: 1KG
- Purity: 95%
- Supply Ability: 500kg
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610798-31-7
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| Company Name: |
Capot Chemical Co.,Ltd.
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571-85586718 |
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+86-571-85864795 |
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China |
| Products Intro: |
Product Name:N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-amine
CAS:610798-31-7
Purity:95% Min. Package:1G;1KG;100KG |
| CB Index: |
60 |
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http://www.capotchem.com |
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Catalog(29797)
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