| | 30562-34-6 Basic information More.. |
| Product Name: | Geldanamycin | | Synonyms: | CP-122634;9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione 9-Carbamate;NSC 212518;GELDANAMYCIN FROM STRE;GeldanaMycin, froM StreptoMyces hygroscopicus var geldanus;GeldanaMycin froM StreptoMyces hygroscopi;2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9,13-dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, 9-carbamate;Geldanamycin [(3R,5R,6S,7R,8E,10R,11R,12Z,14E)-6-Hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate | | CAS: | 30562-34-6 | | MF: | C29H40N2O9 | | MW: | 560.64 | | EINECS: | 999-999-2 | | Mol File: | 30562-34-6.mol |  |
Use
Geldanamycin is benzoquinone ansamycin antibiotic isolated from Streptomyces hygroscopicus. It is a potent antitumor metabolite that acts by binding to the 90-kDa heat-shock protein (Hsp90) essential to maintain the conformation, stability, activity and cellular localisation of several key oncogenic proteins such as ERBB2, C-RAF, CDK4, AKT/PKB, steroid hormone receptors, mutant p53, HIF-1α, survivin and telomerase hTERT.
- Geldanamycin
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- US $0.00 / kg
- 2025-07-16
- CAS:30562-34-6
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 1000kg
- Geldanamycin
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- US $39.00-122.00 / mg
- 2025-07-15
- CAS:30562-34-6
- Min. Order:
- Purity: 99.27%
- Supply Ability: 10g
- Geldanamycin
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- US $0.00 / KG
- 2025-07-07
- CAS:30562-34-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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30562-34-6
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