81098-60-4 Basic information More..
Product Name:Cisapride
Synonyms:(+/-)-4-AMINO-5-CHLORO-N-[1-[(3R*,4S*)-3-(4-FLUOROPHENOXY)PROPYL]-3-METHOXY-4-PIPERIDINYL]-2-METHOXYBENZAMIDE;4-AMINO-5-CHLORO-N-[(3R,4S)-1-[3-(4-FLUOROPHENOXY)PROPYL]-3-METHOXYPIPERIDIN-4-YL]-2-METHOXYBENZAMIDE;Alimix;Benzamide, 4-amino-5-chloro-N-[1-[(3R,4S)-3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxy-, rel-;cis-2-Methoxy-4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]benzamide;Propulsin;Risamal;T 1341
CAS:81098-60-4
MF:C23H29ClFN3O4
MW:465.95
EINECS:279-689-7
Mol File:81098-60-4.mol
81098-60-4

Use

Cisapride 14C labeled at the carbonyl carbon and 3H labeled at the fluorophenyl moiety or at the piperidine ring is investigated using some animals. N- Dealkylation at the nitrogen of the piperidine ring, resulting in the main urinary metabolite norcisapride, and aromatic hydroxylation of the fluorinated phenyl ring are the major metabolic pathways in dogs and humans. Norcisapride excretion accounts for 14% of the dose in dogs and 41-45% in humans. Minor metabolic pathways are O-dearylation of the 4- fluorophenyl group and oxidation on the piperidine ring (rat, rabbits and dogs: Lavrijsen et al. (1986)15).

Cisapride manufacturers

  • Cisapride
  • US $10.00 / Kg/Drum
  • 2023-03-06
  • CAS:81098-60-4
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 10 ton
  • Cisapride
  • US $1.00 / kg
  • 2022-10-18
  • CAS:81098-60-4
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 50000tons
  • Cisapride
  • US $111.00 / g
  • 2022-04-01
  • CAS:81098-60-4
  • Min. Order: 10g
  • Purity: 99%
  • Supply Ability: 26kgs
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