18172-33-3 Basic information More..
Product Name:CYCLOPIAZONIC ACID
Synonyms:-Cyclopiazonic acid / CPA;Cyclopiazonic acid from Penicillium grisefulvum;Cyclopiazonic acid (CPA);Cyclopiazonic acid, FroM PenicilliuM griseofulvuM;(6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one;(6a-alpha,11a,11b-alpha)--10-acetyl-7-dimethyl-11-hydroxy-;9h-pyrrolo(1’,2’:2,3)isoindolo(4,5,6-cd)indol-9-one,2,6,6a,7,11a,11b-hexahydro;(6AA, 10Z, 11AB, 11BA)-6A,7,11A,11B-TETRAHYDRO-10-(1-HYDROXYETHYLIDENE)-7,7- DIMETHYL-6H-PYRROLO [1',2':2,3]ISOINDOLO [4,5,6-CD]INDOLE-9,11 (2H,10H)-DIONE
CAS:18172-33-3
MF:C20H20N2O3
MW:336.38
EINECS:
Mol File:18172-33-3.mol
18172-33-3

Use

Cyclopiazonic acid is a tremorigenic indole produced by several species of Aspergillus and Penicillium. Cyclopiazonic acid is a highly specific inhibitor of calcium ATPase of sarcoplasmic reticulum, altering calcium homeostasis and ATP-dependent calcium transport and resulting in the release of intracellular stored Ca2+ without increasing IP3.

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