Sodium 1-heptanesulfonate is used as an ion-pairing reagent for HPLC, including analyses of peptides and proteins. The anionic sulfonate counterion permits the separation and resolution of positively charged analytes. It is utilized in the analysis of both organic and inorganic small molecule compounds. HPLC analysis of many pharmaceutical products or metabolites commonly incorporates sodium 1-heptanesulfonate. It is also utilized in high performance capillary electrophoresis analysis of peptides.
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