Use
Sodium aurothiomalate is a commonly used gold-based DMARD and is indicated for active progressive
RA. It is administered by deep intramuscular injection. Administration is started with a test dose of 10mg
followed by weekly intervals of 50 mg doses. An improvement is expected to be seen once 300–500 mg
is administered. Treatment should be discontinued if there is no improvement after administering 1 g or
2months. Intervals of administration should be gradually increased to 4weeks in patients in whom an effect can be seen. If any blood disorders or other side effects such as GI bleedings or proteinuria are observed,
sodium aurothiomalate should be discontinued.