848133-17-5(HKI 357)

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Product Name:HKI 357
Synonyms:HKI 357;2-Butenamide, N-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-;(2E)-N-[[4-[[(3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide;Inhibitor,HKI-357,ErbB-1,HER1,inhibit,NSCLCs,Epidermal growth factor receptor,HKI 357,EGFR,ERBB2,HKI357
CAS:848133-17-5
MF:C31H29ClFN5O3
MW:574.05
EINECS:
Mol File:Mol File
848133-17-5
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CAS:848133-17-5
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
CB Index: 60
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Purity:98.00% Package:1 mg;10 mg;100 mg;200 mg;25 mg;5 mg;50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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CAS:848133-17-5
Purity:≥98% by HPLC Remarks:HKI 357 is a potent and irreversible dual inhibitor of ErbB2 (HER2) and EGFR (IC50 = 33 and 34 nM, respectively). It inhibits EGFR autophosphorylation and proliferation of NCI-H1975 cells containing L
CB Index: 65
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CAS:848133-17-5
Purity:>=98%(HPLC) Package:$187.9/5mg;$286.9/10mg;$583.9/25mg;$929.9/50mg;$1484.9/100mg;Bulk package Remarks:98%(HPLC)
CB Index: 58
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