Company Name: |
Hangzhou Huiyi Biotechnology Co., LTD
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Tel: |
0571-89918262 13357170655 |
Email: |
chenlingwei@hizyme.com |
Products Intro: |
Cas:6379-56-2
ProductName:Hygromycin A
Purity: HPLC90%纯度;HPLC90%纯度95% | Package: 100mg;1g;10g;100g
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- Hygromycin B
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- $8.00 / 1KG
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2024-04-09
- CAS:31282-04-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- Hygromycin B
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- $15.00 / 1KG
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2021-07-02
- CAS:31282-04-9
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Hygromycin B
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- $1.00 / 1KG
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2019-07-14
- CAS:31282-04-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 25kg
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| Hygromycin Basic information |
Product Name: | Hygromycin | Synonyms: | hygromycin A;5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-5-hexosulofuranosyl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propenyl]amino]-1-O,2-O-methylene-D-neo-inositol;Antibiotic WS-1627B;D-neo-Inositol, 5-deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-;Homomycin;Hygromycin;Homomycin A;(E)-N-[(3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxy-3a,4,5,6,7,7a-hexahydro-1,3-benzodioxol-5-yl]-3-[4-[(2S,3S,4S,5S)-5-acetyl-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxyphenyl]-2-methylprop-2-enamide | CAS: | 6379-56-2 | MF: | C23H29NO12 | MW: | 511.48 | EINECS: | | Product Categories: | | Mol File: | 6379-56-2.mol | |
| Hygromycin Chemical Properties |
Melting point | 105-109°; mp 110-112° (dec) (Chida) | alpha | D25 -126° (c = 1 in water) | Boiling point | 925.5±65.0 °C(Predicted) | density | 1.60±0.1 g/cm3(Predicted) | storage temp. | -20°C | solubility | DMF: 16 mg/mL,DMSO: 10 mg/mL,Ethanol: 12 mg/mL,PBS (pH 7.2): 10 mg/mL | form | A solid | pka | 8.9(at 25℃) | InChIKey | YQYJSBFKSSDGFO-MZHPCZETNA-N | SMILES | [C@H]12OCO[C@H]1[C@@H](O)[C@H](O)[C@H](NC(=O)/C(/C)=C/C1=CC=C(O[C@H]3[C@@H](O)[C@H](O)[C@@H](C(=O)C)O3)C(O)=C1)[C@@H]2O |&1:0,4,5,7,9,21,22,24,26,34,r| | CAS DataBase Reference | 6379-56-2 |
| Hygromycin Usage And Synthesis |
Description | Aminoglycosides are the most widely used class of antibiotics that target ribosome. Hygromycin B is an aminocyclitol antibiotic. The organism, S. hygroscopicus contains phosphotransferase (HPH) activity, which phosphorylates hygromycin B helping in autoimmunity against the toxic effects of the drug. | Application | Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It has been used to study protein synthesis at the level of the 70S ribosome translocation and mRNA template misreading, as an antiviral agent by selectively penetrating cells rendered permeable by virus infection and inhibiting translation, and as a selection agent for hygromycin resistance gene transformed cells. |
| Hygromycin Preparation Products And Raw materials |
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