Recombinant Human Hgf

Recombinant Human Hgf manufacturers

Recombinant Human Hgf Basic information
Product Name:Recombinant Human Hgf
Synonyms:HUMAN SCATTER FACTOR;HUMAN SF;HGF;HGF, HUMAN;HUMAN HEPATOCYTE GROWTH FACTOR;HUMAN HEPATOPOIETIN;HUMAN HPTA;HEPATOCYTE GROWTH FACTOR
CAS:
MF:
MW:0
EINECS:214-275-1
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Mol File:Mol File
Recombinant Human Hgf Structure
Recombinant Human Hgf Chemical Properties
storage temp. −20°C
form powder
Safety Information
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 22-24/25-26
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
Recombinant Human Hgf Usage And Synthesis
UsesHepatocyte Growth Factor human has been used as a growth factor cocktail to suspend rat fibrogen/thrombin cells. It has also been used to study the tyrosine phosphorylation of MET (MET proto-oncogene, receptor tyrosine kinase) in myxofibrosarcoma cell line.
General DescriptionThe HGF gene spans ~70 kb and consists of 18 exons interrupted by 17 introns. The organization of the human HGF gene is highly homologous to that of human plasminogen. HGF maps to the long arm of human chromosome 7, 7q21.1.
Biochem/physiol ActionsHGF is a multifunctional cytokine that promotes mitogenesis, migration, invasion, and morphogenesis. It is a potent mitogen, stimulating the growth of hepatocytes, renal tubular epithelial cells, epidermal keratinocytes, epidermal melanocytes, Mv1Lu (mink lung epithelial cells), and BALB/MK (mouse keratinocytes). HGF inhibits the growth of B6/F1 (mouse melanoma) cells, KB (human squamous carcinoma) cells, and HepG2 (human hepatoma) cells. HGF is the ligand for the tyrosine kinase receptor encoded by the met proto-oncogene.
Recombinant Human Hgf Preparation Products And Raw materials
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