| Company Name: |
Haihang lndustry Co.,Ltd.
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| Tel: |
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| Email: |
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| Products Intro: |
Cas:41927-89-3
ProductName:FOLINIC ACID CALCIUM SALT PENTAHYDRATE
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| Company Name: |
American Custom Chemicals Corporation
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| Tel: |
858 201 6118 |
| Email: |
sales@acccorporation.com |
| Products Intro: |
Cas:41927-89-3
ProductName:CALCIUM FOLINATE PENTAHYDRATE
Brand：Acccorporation | OriginalID：ING0006721 | Purity：95.00%
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Calcium Folinate Pentahydrate manufacturers
- Calcium folinate
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- $0.00 / 1kg
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2024-04-19
- CAS:1492-18-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20tons
- Calcium folinate
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- $45.00 / 1KG
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2021-08-13
- CAS:1492-18-8
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 500000kgs
- Calcium folinate
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- $15.00 / 1KG
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2021-07-02
- CAS:1492-18-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | Calcium Folinate Pentahydrate Basic information |
| Product Name: | Calcium Folinate Pentahydrate | | Synonyms: | 5-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID CALCIUM SALT;5-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID CALCIUM SALT PENTAHYDRATE;5-FORMYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID CALCIUM SALT PENTAHYDRATE;5-HCO-H4PTEGLU CALCIUM SALT PENTAHYDRATE;CALCIUM FOLINATE PENTAHYDRATE;LEUCOVORIN CALCIUM SALT PENTAHYDRATE;LEUCOVORIN PENTAHYDRATE;FOLINIC ACID CALCIUM SALT PENTAHYDRATE | | CAS: | 41927-89-3 | | MF: | C20H31CaN7O12 | | MW: | 601.58 | | EINECS: | | | Product Categories: | | | Mol File: | 41927-89-3.mol |  |
| | Calcium Folinate Pentahydrate Chemical Properties |
| Melting point | 240-250 °C | | storage temp. | 0-6°C | | solubility | Aqueous (Slightly, Sonicated), Water (Sparingly, Heated, Sonicated) | | form | Solid | | color | Off-White to Pale Yellow | | Stability: | Hygroscopic |
| Provider | Language |
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ACROS
| English |
| | Calcium Folinate Pentahydrate Usage And Synthesis |
| Uses | Anti-anemic (folate deficiency); antidote (to folic acid
antagonists). | | Brand name | Wellcovorin (GlaxoSmithKline). | | Clinical Use | Folinic acid rescue
Enhancement of 5-fluorouracil cytotoxicity in
advanced colorectal cancer
Folate deficiency | | Drug interactions | Potentially hazardous interactions with other drugs
Should not be administered simultaneously with a
folic acid antagonist as this may nullify the effect of
the antagonist.
Cytotoxics: avoid with panitumumab and raltitrexed. | | Metabolism | Folinic acid is a racemate where the L-form (L-5-
formyl-tetrahydrofolate, L-5-formyl-THF), is the active
enantiomer. The major metabolic product of folinic acid
is 5-methyl-tetrahydrofolic acid (5-methyl-THF) which
is predominantly produced in the liver and intestinal
mucosa.
80-90% with the urine (5- and 10-formyltetrahydrofolates
inactive metabolites), 5-8% with the
faeces. |
| | Calcium Folinate Pentahydrate Preparation Products And Raw materials |
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