| Company Name: |
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| Tel: |
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| Email: |
akashpharmaexports@gmail.com |
| Products Intro: |
Cas:59333-67-4
ProductName:Fluoxetine Hcl
Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
|
| Tel: |
|
| Email: |
revanth@cplinc.net |
| Products Intro: |
Cas:59333-67-4
ProductName:Fluoxetine HCL
Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
|
- Fluoxetine
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- $10.00 / 1Kg/Bag
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2021-09-07
- CAS:54910-89-3
- Min. Order: 1Kg/Bag
- Purity: Above 99%
- Supply Ability: 5000kg/month
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| | Fluoxetine Hcl Basic information |
| | Fluoxetine Hcl Chemical Properties |
| Melting point | 158-159°C | | Fp | 9℃ | | storage temp. | -20°C Freezer | | solubility | H2O: 4 mg/mL | | form | solid | | color | white | | BCS Class | 1 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | CAS DataBase Reference | 59333-67-4(CAS DataBase Reference) |
| | Fluoxetine Hcl Usage And Synthesis |
| Description | Fluoxetine Hcl is the hydrochloride salt form of fluoxetine, a diphenhydramine derivative and selective serotonin reuptake inhibitor with antidepressant, anti-anxiety, antiobsessional and antibulimic activity and with potential immunomodulating activity. 
| | Biological Activity | Fluoxetine Hcl is a selective serotonin reuptake inhibitor. Binds to the human 5-HT transporter with a Ki of 0.9 nmol/l and is between 150- and 900-fold selective over 5-HT1A, 5-HT2A, H1, α1, α2-adrenergic, and muscarinic receptors. Fluoxetine also inhibits assembly and activation of the NLRP3-ASC inflammasome and prevents degeneration of retinal pigmented epithelium (RPE) cells in an animal model of dry age-related macular degeneration (AMD). | | Mechanism of action | Upon administration, fluoxetine binds to the presynaptic serotonin (5-HT) receptor resulting in negative allosteric modulation of the receptor complex, thereby blocking recycling of serotonin by the presynaptic receptor. Inhibition of serotonin reuptake by fluoxetine enhances serotonergic function through serotonin accumulation in the synaptic space, resulting in long-term desensitization and downregulation of 5-HT receptors, preventing 5-HT-mediated signaling and leading to antidepressant, anti-anxiety, antiobsessional and antibulimic effects. | | Side effects | Common effects include: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. |
| | Fluoxetine Hcl Preparation Products And Raw materials |
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