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| | Norfloxacinehydrochloride Basic information |
| Product Name: | Norfloxacinehydrochloride | | Synonyms: | NorfloxacineHCl;Norfloxacinehydrochloride;Hydrochloric acid and norfloxacin;Norfloxacinehydrochloride USP/EP/BP;Norfloxacin hydrochloride (MK-0366);3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride (1:1);1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-Quinolinecarboxylic acid hydrochloride (1:1);1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazin-1-yl-quinolin-3-carboxylic acid HCl | | CAS: | 68077-27-0 | | MF: | C16H19ClFN3O3 | | MW: | 355.7917632 | | EINECS: | | | Product Categories: | | | Mol File: | 68077-27-0.mol |  |
| | Norfloxacinehydrochloride Chemical Properties |
| Melting point | >300 °C | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Powder |
| | Norfloxacinehydrochloride Usage And Synthesis |
| Uses | Norfloxacin hydrochloride (MK-0366 hydrochloride) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase. | | References | [1] Nelson JM, et al. Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story. Clin Infect Dis. 2007 Apr 1;44(7):977-80. Epub 2007 Feb 14. DOI:10.1086/512369
[2] Padeiskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36. PMID:15002177
[3] Rafalsky V, et al. Quinolones for uncomplicated acute cystitis in women. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD003597. DOI:10.1002/14651858.CD003597.pub2 |
| | Norfloxacinehydrochloride Preparation Products And Raw materials |
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