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| | 6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Basic information |
| Product Name: | 6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone | | Synonyms: | LEVOSIMENDAN DAZINONES INTERMEDIATES;6-(4-AMINOPHENYL)-4,5-DIHYDRO-5-METHYL-3(2H)PYRIDAZINONE;6-(4-AMINO-PHENYL)-5-METHYL-4,5-DIHYDRO-2H-PYRIDAZIN-3-ONE;6-(4''-AMINOPHENYL)-4,5-DIHYDRO-5-METHYLPYRIDAZIN-3-ONE;ICI 109,081;6-(p-Aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone;6-(4-AMINOPHENYL)-5-METHYLPYRIDAZIN-3(2H)ONE, 98+%;1,4-Dihydro-4-methyl-3-(4-aminophenyl)pyridazine-6(5H)-one | | CAS: | 36725-28-7 | | MF: | C11H13N3O | | MW: | 203.24 | | EINECS: | | | Product Categories: | (intermediate of levosimendan) | | Mol File: | 36725-28-7.mol |  |
| | 6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Chemical Properties |
| Melting point | 194.0 to 198.0 °C | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) | | form | Solid | | pka | 13.90±0.60(Predicted) | | color | Pale Yellow to Brown | | InChI | InChI=1S/C11H13N3O/c1-7-6-10(15)13-14-11(7)8-2-4-9(12)5-3-8/h2-5,7H,6,12H2,1H3,(H,13,15) | | InChIKey | NWUOGOISBQCNKQ-UHFFFAOYSA-N | | SMILES | C1(=O)NN=C(C2=CC=C(N)C=C2)C(C)C1 | | CAS DataBase Reference | 36725-28-7(CAS DataBase Reference) |
| | 6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Usage And Synthesis |
| Uses | AMDP3 (4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one) acts as a cardiac troponin effecter, resulting in activation of cardiac muscle contractions. It’s an analogue to Levosimendan (L378000), positive inotropic agent with vasodilating activity. |
| | 6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Preparation Products And Raw materials |
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