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Euphorbiasteroid

Euphorbiasteroid Suppliers list
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:Euphorbiasteroid
CAS:28649-59-4
Purity:99% Package:25KG
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Euphobiasteroid
CAS:28649-59-4
Purity:HPLC>=98% Package:20mg/100mg
Company Name: career henan chemical co
Tel: +86-0371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Euphorbiasteroid
CAS:28649-59-4
Purity:99% Package:25KG;100USD
Company Name: Chengdu GLP biotechnology Co Ltd
Tel: 028-87075086 13350802083
Email: scglp@glp-china.com
Products Intro: Product Name:Euphorbiasteroid
CAS:28649-59-4
Purity:0.98 Package:20MG;50MG;100MG;1G;5G;1KG
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: +8618080483897
Email: sales@biopurify.com
Products Intro: Product Name:Euphorbiasteroid
CAS:28649-59-4
Purity:0.98 Package:10mg;20mg;50mg;100mg;500mg Remarks:Can Be Customized in Bulk

Euphorbiasteroid manufacturers

  • Euphorbiasteroid
  • Euphorbiasteroid pictures
  • $0.00 / 25KG
  • 2023-08-30
  • CAS:28649-59-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50000KG/month
  • Euphobiasteroid
  • Euphobiasteroid pictures
  • $0.00 / 20mg
  • 2023-02-24
  • CAS:28649-59-4
  • Min. Order: 20mg
  • Purity: ≥98%(HPLC)
  • Supply Ability: 10 g
  • Euphorbiasteroid
  • Euphorbiasteroid pictures
  • $1.00 / 1KG
  • 2021-07-13
  • CAS:28649-59-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt

Related articles

Euphorbiasteroid Basic information
Product Name:Euphorbiasteroid
Synonyms:Daughter son sterol;6,20-Epoxylathyrol phenylacetate diacetate;Benzeneacetic acid (1aR,2'R,2E,4aR,6S,7S,7aR,8S,11aS)-4a,8-bis(acetyloxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-7-yl ester;Benzeneacetic acid 4a,8-bis(acetyloxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-7-yl ester;Euphorbia factor L1;Euphorbiasteroid, 98%, from Leptochloa chinensis (L.) Nees;(1aS,2E,4aR,6S,7S,7aS,8S,9R,11aS)-4a,8-bis(acetyloxy)-1,1,3,6-tetramethyl-4-oxo-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-7-yl phenylacetate;(1aS,2E,4aR,6S,7S,7aS,8S,9R,11aS)-4a,8-bis(acetyloxy)-1,1,3,...
CAS:28649-59-4
MF:C32H40O8
MW:552.66
EINECS:
Product Categories:
Mol File:28649-59-4.mol
Euphorbiasteroid Structure
Euphorbiasteroid Chemical Properties
Melting point 199~200℃
Boiling point 633.1±55.0 °C(Predicted)
density 1.23
storage temp. 4°C, protect from light
solubility DMSO:15.0(Max Conc. mg/mL);27.14(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);9.05(Max Conc. mM)
form A crystalline solid
Safety Information
Safety Statements 24/25
HS Code 29061990
MSDS Information
Euphorbiasteroid Usage And Synthesis
UsesEuphorbiasteroid is a compound used to induce HL-60 cells to apoptosis via promoting Bcl/Bax apoptotic signaling pathway in a dose-dependent manner.
Biological FunctionsEuphorbiasteroid, Euphorbia Factor L1 (EFL1) to be specific, with a tricyclic terpenoid skeleton, consisting of fused five-, eleven- and three-membered rings, is a diterpenoid isolated from the seeds of Euhporbia lathyris L. It is reported EFL1 could be helpful to reduces the expression of Bcl-2, PI3K, AKT and mTOR protein and mRNA, upregulates cleaved caspase-9 and caspase-3 levels, but shows no effect on pro-caspase-9 and pro-caspase-3. EFL1 also could induce apoptosis, and possess anticancer, antiadipogenesis, antiosteoclastogenesis and multi-drug resistance-modulating effect.
Euphorbiasteroid showed effects on adipogenesis of 3T3-L1 pre-adipocytes. Euphorbiasteroid also has the potential to reverse P-glycoprotein (P-gp)-mediated multi-drug resistance (MDR) by using the drug-sensitive human sarcoma cell line MES-SA and its MDR counterpart MES-SA/Dx5.EFL1 inhibited osteoclastogenesis and induced osteoclast apoptosis. Euphorbiasteroid suppressed osteoclast formation and bone resorption at both initial and terminal differentiation stages.
Euphorbiasteroid Preparation Products And Raw materials
Tag:Euphorbiasteroid(28649-59-4) Related Product Information
Euphorbia factor L7b beta-Sitosterol Dodecanoic acid ingenol ester Ingenol mebutate 17-Hydroxyisolathyrol 20-DEOXYINGENOL (6R)-6,6aβ,7aβ,8,9,12,12a,12bβ-Octahydro-12α,12aα-dihydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d]-1,3-dioxin-13-one Euphorbia factor L1 euphorbiafactor L2 DIACETYL BENZOYL LATHYROL Ingenol (1aR,7bR)-1aα,2,7aα,13,14,14aα-Hexahydro-1,1,6,6,9,9,11,13α-octamethyl-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin-15-one Euphorbiasteroid TRANS-CYCLODODECENE