Sign in | Register | china | japan | germany

Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]-

Request For Quotation
Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]- Suppliers list
Company Name: Jilin Province Woda Biotechnology Co., Ltd.  
Tel: 13504435624
Email: 1927928688@qq.com
Products Intro: Product Name:TD-802
CAS:2760703-21-5
Purity:98%
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:TD-802
CAS:2760703-21-5
Purity:98%+ HPLC Package:10mg，500mg，1g，2g，5g，10mg，more
Company Name: Shanghai Fine Biotech Co.，Ltd  
Tel: 18221172427
Email: sale@fine-biotech.com
Products Intro: Product Name:TD-802
CAS:2760703-21-5
Purity:98%HPLC Package:100mg;250mg;1g;5g,10g;25g;100g
Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]- Basic information
Product Name:Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]-
Synonyms:Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]-;TD-802
CAS:2760703-21-5
MF:C52H61ClN10O6
MW:957.56
EINECS:
Product Categories:
Mol File:2760703-21-5.mol
Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]- Structure
Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]- Chemical Properties
density 1.43±0.1 g/cm3(Predicted)
pka10.75±0.40(Predicted)
Safety Information
MSDS Information
Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]- Usage And Synthesis
UsesTD-802 (Compound 33c) is an androgen receptor (AR) PROTAC degrader with good microsomal stability. TD-802 has good antitumor efficacy in vivo and can be used for metastatic castration-resistant prostate cancer research[1].
References[1] Takwale AD, et al. Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimeras. Eur J Med Chem. 2020 Dec 15;208:112769. DOI:10.1016/j.ejmech.2020.112769
Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]- Preparation Products And Raw materials
Tag:Benzamide, N-[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[7-[[1-[3-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-4-oxo-1,2,3-benzotriazin-6-yl]-4-piperidinyl]carbonyl]-7-azaspiro[3.5]non-2-yl]-1-piperazinyl]-(2760703-21-5) Related Product Information
  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.