CYCLO(-PRO-VAL)

CYCLO(-PRO-VAL) Suppliers list
Company Name: BOC Sciences
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Products Intro: Product Name:cyclo(L-Pro-L-Val)
CAS:2854-40-2
Purity:>98% by HPLC Remarks:A diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus. It is a secondary metabolite found in various marine fungi and bacteria. It is capable of activating N-acy
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Products Intro: Product Name:CYCLO(-PRO-VAL)
CAS:2854-40-2
Purity:98% Min. Package:5KG;1KG
Company Name: Chengdu Youngshe Chemical Co., Ltd.
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Products Intro: Product Name:Cyclo(Pro-Val)
CAS:2854-40-2
Purity:0.98 Package:1G;10G
Company Name: LEAP CHEM CO., LTD.
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Products Intro: Product Name:cyclo(L-Val-L-Pro)
CAS:2854-40-2
Package:1g; 5g; 25g; 1kg; 5kg; 25kg
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
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Products Intro: Product Name:Cyclo(-Pro-Val)
CAS:2854-40-2
Purity:NLT 98% Remarks:MC546323
CYCLO(-PRO-VAL) Basic information
Product Name:CYCLO(-PRO-VAL)
Synonyms:CYCLO(-PRO-VAL);(3S,8aS)-3-Isopropyl-6,7,8,8aα-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione;(3S,8aS)-3β-Isopropyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione;(3S,8aS)-Octahydro-3-(1-methylethyl)pyrrolo[1,2-a]pyrazine-1,4-dione;(3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione;Cyclo(L-Pro-L-Val-);Cyclo(L-Val-L-Pro-);Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aS)-
CAS:2854-40-2
MF:C10H16N2O2
MW:196.25
EINECS:
Product Categories:
Mol File:2854-40-2.mol
CYCLO(-PRO-VAL) Structure
CYCLO(-PRO-VAL) Chemical Properties
Melting point 190-192 °C
Boiling point 420.7±34.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly, Sonicated), Methanol (Slightly)
form Solid
pka13.15±0.40(Predicted)
color White to Off-White
Safety Information
MSDS Information
CYCLO(-PRO-VAL) Usage And Synthesis
DescriptionCyclo(L-Pro-L-Val) is a diketopiperazine that has been found in the marine sponge T. ignis, the bacterium B. pumilus, and the fungus A. fumigatus, among others. It is active against the bacteria S. aureus and B. subtilis (MICs = 16.3 and 18.2 μg/ml, respectively) but not E. coli (MIC = >20 μg/ml). Cyclo(L-Pro-L-Val) inhibits activation of a LuxR-dependent E. coli biosensor by the quorum-sensing molecule 3-oxo-hexanoyl-homoserine lactone (IC50 = 0.4 mM) and activates violacein pigment production in the LuxR-dependent C. violaceum acyl homoserine lactone reporter strain CV026. However, it does not activate or inhibit lacZ-based reporter fusions in S. liquefaciens or A. tumefaciens.
UsesCyclo(L-prolyl-L-valyl) is a metabolite found in various marine fungi and bacteria. It is a diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus.
UsesCyclo(L-Pro-L-Val) is a diketopiperazine formed by the fusion of valine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Pro-L-Val) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Pro-L-Val) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of the cyclo(L-Pro-L-Val) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.
CYCLO(-PRO-VAL) Preparation Products And Raw materials
Preparation Products9-(2'-ACETOXYETHOXYMETHYL)-GUANINE
Tag:CYCLO(-PRO-VAL)(2854-40-2) Related Product Information
cyclo(Pro-Lys) cyclo(Pro-Asn) CYCLO(-PHE-PRO) cyclo(Pro-Gln) cyclo(Pro-Cys) Cyclo(-Phe-Tyr) CYCLO(-MET-PRO) cyclo(Pro-Ser) cyclo(Pro-Asp) cyclo(Pro-Glu) MACULOSIN CYCLO(-PRO-VAL) (R)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-1(2H)-ONE (3S)-3-ISOPROPYL-1-METHYLPIPERAZINE (2S)-ISOPROPYLPIPERAZINE (S)-3-Isopropyl-2,5-piperazinedione 3-ISOPROPYL-PIPERAZIN-2-ONE