血纤维蛋白肽B
| 中文名称 | 血纤维蛋白肽B |
|---|---|
| 中文同义词 | 纤维蛋白肽B;[GLU1]-FIBRINOPEPTIDEB 人;人[GLU1] FIBRINOPEPTIDE B肽;[GLU1]-纤维蛋白肽B;GLU1]-FIBRINOPEPTIDE B 衍生自纤维蛋白肽B |
| 英文名称 | GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG |
| 英文同义词 | GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG;GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-SER-ALA-ARG;(GLU1)-FIBRINOPEPTIDE B;[GLU1]-FIBRINOPEPTIDE B HUMAN;H-GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG-OH;FGB;Fibrinogen beta chain;Monoclonal Anti-FGB antibody produced in mouse |
| CAS号 | 103213-49-6 |
| 分子式 | C66H95N19O26 |
| 分子量 | 1570.57 |
| EINECS号 | |
| 相关类别 | 微生物;多肽;标准品;Blood;Clotting FactorsProteins and Derivatives;Coagulation Proteins and ReagentsPeptides for Cell Biology;Extracellular Matrix Peptides (ECM);Fibrinogen Fragments;Immune Cell Signaling and Blood;Plasma&Blood Proteins |
| Mol文件 | 103213-49-6.mol |
| 结构式 |  |
血纤维蛋白肽B 性质
| 密度 | 1.56±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | -20°C |
| 形态 | 粉末 |
| 酸度系数(pKa) | 3.33±0.10(Predicted) |
| 水溶解性 | Soluble in water at 1mg/ml |
[Glu1]-Fibrinopeptide B 衍生自纤维蛋白肽B氨基酸残基1-14。人纤维蛋白肽B（hFpB）是来自纤维蛋白原B β链的凝血酶衍生的蛋白水解裂解产物，可用于刺激中性粒细胞 (PMN)，单核细胞和成纤维细胞。
hFpB causes directed cell migration of PMN and fibroblasts that is optimal at approximately 10 nM. hFpB causes a rapid, dose-dependent increase in PMN cytoskeletal associated actin, but unlike fMLP, hFpB does not cause PMN aggregation, release of lysosomal enzymes (lysozyme and beta-glucuronidase), or the production of superoxide anion. These results suggest that hFpB may have a role in recruiting PMN and fibroblasts at sites of fibrin deposition and turnover. The capacity of hFpB to cause PMN chemotaxis without causing concurrent release of lysosomal enzymes or the production of superoxide anion is further evidence for the complexity of PMN responses to chemotactic agents.
安全信息
| WGK Germany | 3 |
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| 提供商 | 语言 |
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-P0308 | 血纤维蛋白肽B [Glu1]-Fibrinopeptide B | 103213-49-6 | 500 μg | 1200元 |
| 2024/01/25 | HY-P0308 | 血纤维蛋白肽B [Glu1]-Fibrinopeptide B | 103213-49-6 | 1mg | 1800元 |