1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1)

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1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1) Suppliers list
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1) Basic information
Product Name:1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1)
Synonyms:1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1);N-[2R-hydroxy-1R-(hydroxymethyl)-3E-heptadecenyl]-2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol,monohydrochloride
CAS:2319882-09-0
MF:C23H31N5O6.ClH
MW:509.98
EINECS:
Product Categories:
Mol File:2319882-09-0.mol
1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1) Structure
1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1) Chemical Properties
solubility DMF: 20 mg/ml
DMSO: 10 mg/ml
Ethanol: 20 mg/ml
Ethanol: PBS(pH 7.2) (1:1): 0.5 mg/ml
Safety Information
MSDS Information
1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1) Usage And Synthesis
UsesNBD-FTY720 phenoxy hydrochloride is a fluorescently-labeled analog of FTY720. FTY720 (HY-12005) is a potent sphingosine 1-phosphate (S1P) receptors modulator[1].
References[1] Rolin J, et al. FTY720 and SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release. Cancer Immunol Immunother. 2010, 59(4), 575-586. DOI:10.1007/s00262-009-0775-7
[2] V. BRINKMANN. The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors*[J]. The Journal of Biological Chemistry, 2002, 10 1: 21453-21457. DOI: 10.1074/jbc.c200176200
[3] SHAUN M HONIG. FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes.[J]. Journal of Clinical Investigation, 2003, 111 5: 627-637. DOI: 10.1172/jci16200
[4] S. PAYNE. The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors.[J]. Blood, 2007, 109 3 1: 1077-1085. DOI: 10.1016/j.jaci.2006.12.597
1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1) Preparation Products And Raw materials
Tag:1,3-Propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-, hydrochloride (1:1)(2319882-09-0) Related Product Information
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