Chlorantraniliprole Suppliers list
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Products Intro: Product Name:Chlorantraniliprole
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G
Tel: +8613454675544
Products Intro: Product Name:Chlorantraniliprole
Company Name: Wuhan TCASChem Technology Co., Ltd.  
Tel: 027-86697669 13986148687
Products Intro: Product Name:Chlorantranilipol
Purity:96% Package:5g,10g,25g,100g
Company Name: Shanghai Macklin Biochemical Co.,Ltd.  
Tel: 15221275939
Products Intro: Product Name:Chlorantraniliprole
Purity:分析标准品 Package:25mg
Company Name: U-Chemo Scientific(Shanghai) Co.,Ltd  
Tel: 021-58380326 13585932672
Products Intro: Product Name:Chlorantraniliprole
Purity:98% Package:1G/25G;100G;1KG;100KG Remarks:PP156
Chlorantraniliprole Basic information
Product Name:Chlorantraniliprole
Synonyms:CHLORANTRANILIPROLE;Rynaxpyr;DPX E2Y45;Chlorantraniliprole 95%;Chlorantraniliprole Standard;Coragen;Chlorantraniliprole 95% (Rynaxypyr, Coragen);Chlorantraniliprole Solution, 1000ppm
Product Categories:pesticide;Agro-Products
Mol File:500008-45-7.mol
Chlorantraniliprole Structure
Chlorantraniliprole Chemical Properties
Melting point approximate 225℃ (dec.)
Boiling point 526.6±50.0 °C(Predicted)
density 1.66±0.1 g/cm3(Predicted)
storage temp. 2-8°C
CAS DataBase Reference500008-45-7
EPA Substance Registry System1H-Pyrazole-5-carboxamide, 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)- (500008-45-7)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37
Safety Statements 26
Hazardous Substances Data500008-45-7(Hazardous Substances Data)
MSDS Information
Chlorantraniliprole Usage And Synthesis
DescriptionChlorantraniliprole (Rynaxpyr) is an insecticide of the ryanoid class. It is a new compound by DuPont belonging to a new class of selective insecticides (anthranilic diamides) featuring a novel mode of action (group 28 in the IRAC classification). It is the first anthranilic diamide registered for use on turfgrass and landscape ornamentals. It is used to control a broad spectrum of pests including cabbage loopers, corn borers, Colorado potato beetle, European grapevine moth, armyworms and cutwormson a range of crops including potatoes and cotton. Its mechanism of action is through activating the insect ryanodine receptors (RyRs), further stimulating the release and depletion of intracellular calcium stores from the sarcoplasmic reticulum of muscle cells, causing impaired muscle regulation, paralysis and ultimately death of sensitive species.
DescriptionChlorantraniliprole is an anthranilic diamide insecticide and agonist of ryanodine receptors located on the sarcoplasmic reticulum in muscle and endoplasmic reticulum in non-muscle cells. It binds to a different site than ryanodine on the receptor and stimulates the release of calcium from intracellular stores with EC50 values ranging from 40 to 50 nM for P. americana neurons and H. virescens or D. melanogaster recombinant ryanodine receptors. It is highly selective for insect over mammalian ryanodine receptors (EC50s = 14,000 nM, >100 μM, and >100 μM for C2C12 mouse, PC12 rat, and IMR32 human cells, respectively). Chlorantraniliprole is active against insects of the order Lepidoptera, including larvae of the fall armyworm (S. frugiperda), diamondback moth (P. xylostella), and tobacco budworm (H. virescens) with EC50 values of 0.02, 0.01, and 0.05 ppm, respectively, and of the orders Coleoptera, Diptera, and Isoptera. Formulations containing chlorantraniliprole have been used in agriculture to control moths, beetles, and caterpillars among other insects.
Chemical PropertiesWhite crystal, specific gravity (for liquid) 1.507g/mL, melting point 208-210℃, decomposition temperature 330℃, vapor pressure (under 20~25) 6.3×1012Pa, solubility (under 20~25, mg/L): water 1.023, acetone 3.446, methanol 1.714, acetonitrile 0.711, ethyl acetate 1.144. Chlorfenvinphos It is highly efficient and broad-spectrum, and has good control effect on Lepidoptera of Noctuidae, stem borer moths, fruit moths, leaf roller moths, pink moths, vegetable moths, wheat moths, and fine moths, etc. It can also control Sphingidae weevils, leaf beetles; Diptera subterranean flies; sooty fly and many other non-lepidopteran pests.
UsesChlorantraniliprole is a pyrazolylpyridine insecticide and an activator of insect ryanodine receptor. Used in Pesticide detection. (Solution)
UsesChlorantraniliprole is a pyrazolylpyridine insecticide and an activator of insect ryanodine receptor.
DefinitionChEBI: Chlorantraniliprole is a carboxamide resulting from the formal condensation of the carboxylic acid group of 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid with the primary amino group of 2-amino-5-chloro-N,3-dimethylbenzamide. The first of the anthranilic diamide insecticides, it is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes. It has a role as a ryanodine receptor agonist. It is an organobromine compound, a member of pyridines, a member of pyrazoles, a pyrazole insecticide, a member of monochlorobenzenes and a secondary carboxamide.
PreparationChlorantraniliprole was synthesized by reaction of 3-bromo-1-(3-chloropyridin-2-pyridinyl)-1H-pyrazole-5carboxylic acid with 2-amino-5-chloro-3-methylbenzoic acid.3-bromo-1-(3-chloropyridin-2-pyridinyl)-1H-pyrazole5-carboxylic acid was prepared by reaction of maleic anhydride with 2,3-dichloropyridine as starting materials in eight steps.2-Amino-5-chloro-3-methylbenzoic acid was prepared by reaction of 2-amino-3-methylbenzoic acid in one step.The structure of target compound was conf irmed by 1H NMR.Total yield was 36.3%(calculated with 2,3-dichloropyridine),and purity determined by HPLC was over 95%.
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