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Product Name: | BT11 | Synonyms: | BT11;Methanone, 1,1'-(1,4-piperazinediyl)bis[1-[6-(1H-benzimidazol-2-yl)-2-pyridinyl]-;[4-[6-(1~{H}-benzimidazol-2-yl)pyridine-2-carbonyl]piperazin-1-yl]-[6-(1~{H}-benzimidazol-2-yl)pyridin-2-yl]methanone;BT11;BT 11;BT-11, >98%;piperazine-1,4-diylbis((6-(1H-benzo[d]imidazol-2-yl)pyridin-2-yl)methanone);Omilancor (BT-11) | CAS: | 1912399-75-7 | MF: | C30H24N8O2 | MW: | 528.56 | EINECS: | | Product Categories: | | Mol File: | 1912399-75-7.mol | ![BT11 Structure](CAS/20200515/GIF/1912399-75-7.gif) |
Boiling point | 923.4±75.0 °C(Predicted) | density | 1.424±0.06 g/cm3(Predicted) | pka | 10.24±0.10(Predicted) |
Biological Activity | BT11 is an orally active compound that binds to lanthionine synthetase C-like 2 (LANCL2) with a Kd value of 7.7 μM and can be used for the treatment of inflammatory bowel disease. | in vivo | Oral administration of 8 mg/kg/day BT-11 to mice attenuates colitis. In the drug safety testing experiment in rats, oral high concentrations of BT-11 have good safety (detection concentration up to 1000 mg/kg/day). | target | Target | Value | LANCL2 () | table>
| BT11 Preparation Products And Raw materials |
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Tag:BT11(1912399-75-7)
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