INTEGERRIMINE

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INTEGERRIMINE Basic information
Product Name:INTEGERRIMINE
Synonyms:(15E)-12-Hydroxysenecionan-11,16-dione;(20E)-12-Hydroxysenecionan-11,16-dione;Intergerrimine;Squalidine;INTEGERRIMINE;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3E,5R,6R,14aR,14bR)-;Pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl(1,6)dioxacyclododecino(2,3,4-gh)-;(-)-Integerrimine
CAS:480-79-5
MF:C18H25NO5
MW:335.39
EINECS:
Product Categories:
Mol File:480-79-5.mol
INTEGERRIMINE Structure
INTEGERRIMINE Chemical Properties
Melting point 172°C
Boiling point 472.03°C (rough estimate)
density 1.2250 (rough estimate)
refractive index 1.5100 (estimate)
LogP-1.504 (est)
Safety Information
RIDADR 1544
HazardClass 6.1(b)
PackingGroup III
MSDS Information
INTEGERRIMINE Usage And Synthesis
DescriptionA pyrrolizidine alkaloid present in several species of Senecio and Crotalaria, being first obtained from S. integerrirnus Nutt. It yields a crystalline picrate, m.p. 224°C and on alkaline hydrolysis forms retronecine and integerrinecic acid, ClOH160 S, m.p. 132°C which is dibasic.
UsesIntegerrimine is a pyrrolizidine alkaloid from Senecio leucanthemifolius poiret which displays antimicrobial activity.
DefinitionChEBI: Integerrimine is a macrolide.
ReferencesManske., Can. 1. Res., 17B, 1,8 (1939) Adams, van Doulen.,J. Arner. Chern. Soc., 75,4631 (1953) Gellest, Mate., Austral. 1. Chern., 17, 158 (1964)
INTEGERRIMINE Preparation Products And Raw materials
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