COLISTIN

COLISTIN Suppliers list
Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: 15013857715
Email: admin@nexconn.com
Products Intro: Product Name:COLISTIN
CAS:1066-17-7
Purity:0.97 Package:500G;1KG;25KG
Company Name: QUALITY CONTROL CHEMICALS INC.
Tel: (323) 306-3136
Email: orders@qcchemical.com
Products Intro: Product Name:Polymyxin E1 sulfate
CAS:1066-17-7
Purity:95% Package:10mg;25mg;50mg;100mg;250mg Remarks:Brand: QCC CAT#QP120501
Company Name: BOC Sciences
Tel: 1-631-619-7922
Email: inquiry@bocsci.com
Products Intro: Product Name:Polymyxin E complex
CAS:1066-17-7
Purity:>95%
Company Name: career henan chemical co
Tel: 0086-371-86658258
Email: factory@coreychem.com
Products Intro: Product Name:COLISTIN
CAS:1066-17-7
Purity:99% Package:1KG;7USD
Company Name: BOC Sciences  
Tel:
Email: info@bocsci.com
Products Intro: Product Name:Polymyxin E complex
CAS:1066-17-7

Lastest Price from COLISTIN manufacturers

  • COLISTIN
  • US $7.00 / KG
  • 2020-01-10
  • CAS:1066-17-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
COLISTIN Basic information
Neurotoxicity and Nephrotoxicity
Product Name:COLISTIN
Synonyms:colisticina;colomycin;coly-mycin;colymysins;kangdisu;kolimitsin;totazina;COLISTIN
CAS:1066-17-7
MF:C52H98N16O13
MW:1155.43
EINECS:213-907-3
Product Categories:
Mol File:1066-17-7.mol
COLISTIN Structure
COLISTIN Chemical Properties
Boiling point 807.67°C (rough estimate)
density 1.1050 (rough estimate)
refractive index 1.6700 (estimate)
CAS DataBase Reference1066-17-7
Safety Information
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
MSDS Information
COLISTIN Usage And Synthesis
Neurotoxicity and NephrotoxicityColistin is an antibiotic which is being used more commonly now than when it was introduced because of its activity against multiresistant Gram-negative bacteria, especially Acinetobacter baumanii and Enterobacteriaceae producing extended spectrum β-lactamases. It had a bad reputation due to reports of neurotoxicity and nephrotoxicity. Recent studies have shown lower rates of nephrotoxicity than previously reported. However, in one of these reports, 7/42 patients with high serum creatinine values prior to colistin treatment developed renal failure.
UsesPolymyxin E (colistin) is a complex of closely related cyclic peptides E1 and E2, with additional minor analogues. Polymyxin E is produced by Bacillus polymyxa var. colistinus, and is a highly basic, atypical cyclic peptide which incorporates the unusual amino acid, diaminobutyric acid. Head-to-tail coupling of lysine completes the macrocycle. Balancing the polar cyclic peptide is a hydrophobic tail with short chain fatty acids. Polymyxin E is a broad spectrum antibiotic active against Gram negative bacteria. The mechanism of action involves disruption of the bacterial outer membrane by a detergent-like effect.
Brand nameColy-Mycin (Monarch).
COLISTIN Preparation Products And Raw materials
Raw materialsColistin sulfate
Tag:COLISTIN(1066-17-7) Related Product Information
COBALT ETHYLENE DIAMINE CHLORIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) COLISTIN Cupric acetylacetonate 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE TERT-BUTYL ISOCYANIDE 2,4-PENTANEDIONE, SILVER DERIVATIVE METHYL ISOCYANOACETATE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) BENZYL ISOCYANIDE Ferric acetylacetonate COBALT(II) ACETYLACETONATE N-BUTYLISOCYANIDE PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Ethyl isocyanoacetate Aluminum acetylacetonate Tosylmethyl isocyanide