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2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one

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Company Name: Hubei Jusheng Technology Co.,Ltd.
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Products Intro: Product Name:2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
CAS:27277-00-5
Purity:0.99 Package:5KG;1KG Remarks:C9H13N5O
Company Name: CONIER CHEM AND PHARMA LIMITED
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Products Intro: Product Name:2-amino-6-methyl-4-propyl-(1,2,4)triazolo(1,5-a)pyrimidin-5-one
CAS:27277-00-5
Purity:0.99 Package:1kg
Company Name: career henan chemical co
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Products Intro: Product Name:2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
CAS:27277-00-5
Purity:99% Package:1KG;1USD
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
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Products Intro: CAS:27277-00-5
Purity:98% Package:5g; 25g; 100g; 500g; 1kg; 25kg
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Products Intro: Product Name:2-Amino-6-methyl-4-propyl-4H-[1,2,4] triazole-[1,5-a] pyrimidone-5-one
CAS:27277-00-5
Purity:0.99 Package:1kg,5kg,25kgs,200kgs;bulk

2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one manufacturers
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Basic information
Product Name:2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
Synonyms:2-AMINO-6-METHYL-4-PROPYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-5(4H)-ONE;2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4] TRIAZOLE-[1,5-A] PYRIMIDINE-5-ONE;2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4]TRIAZOLO-[1,5-A]PYRIMIDIN-5-ONE;2-AMINO-6-METHYL-5-OXO-4-N-PROPYL-4,5-DIHYDRO-S-TRIAZOLE[1,5-A]PYRIMIDINE;ICI 63197;2,4]triazolo[1,5-a]pyrimidin-5(4h)-one,2-amino-6-methyl-4-propyl-[;2-Amio-6-methyl-4-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one;2-AMINO-6-METHYL-5-OXO-4-N-PROPYL-4,5-DIHYDRO-S-TRIAZOLE[1,5-α]PYRIMIDIN
CAS:27277-00-5
MF:C9H13N5O
MW:207.23
EINECS:248-383-5
Product Categories:Cyclic Nucleotide related
Mol File:27277-00-5.mol
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Structure
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Chemical Properties
Melting point 161.8-163 °C
Boiling point 459.9±28.0 °C(Predicted)
density 1.44±0.1 g/cm3(Predicted)
vapor pressure 0.004Pa at 25℃
storage temp. 2-8°C
solubility DMSO: 13 mg/mL
form solid
pka2.96±0.40(Predicted)
color white
Water Solubility 5.7g/L at 20℃
InChIKeyUQDVRVNMIJAGRK-UHFFFAOYSA-N
LogP0.49 at 20℃
CAS DataBase Reference27277-00-5(CAS DataBase Reference)
EPA Substance Registry System2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo-(1,5-a)-pyrimidin-5-one (27277-00-5)
Safety Information
RIDADR 2811
WGK Germany 1
HazardClass 6.1(b)
PackingGroup III
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Usage And Synthesis
UsesICI 63197 is a specific cAMP phosphodiesterase (PDE) inhibitor. It is potent in anatagonizing reserpine-induced hypothermia. potent PDE4 inhibitor.
DefinitionChEBI: 2-amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one is a member of triazolopyrimidines.
Flammability and ExplosibilityNot classified
Biological ActivityPotent phosphodiesterase (PDE) 4 inhibitor (IC 50 = 35 nM for inhibition of [ 3 H]-rolipram binding to rat brain). Antidepressant following systemic administration in vivo .
Biochem/physiol ActionsPhosphodiesterase IV (PDE 4) inhibitor
storage+4°C
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Preparation Products And Raw materials
Tag:2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one(27277-00-5) Related Product Information
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