| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Purity:purified immunoglobulin, buffered aqueous solution Remarks:affinity isolated antibody, buffered aqueous solution
|
| Company Name: |
Fluorochem Ltd
|
| Tel: |
(01457) 868921 (4 lines) |
| Email: |
vernam@fluorochem.co.uk |
| Products Intro: |
|
| Company Name: |
Fluorochem Ltd.
|
| Tel: |
+44 1457 868921 |
| Email: |
enquiries@fluorochem.co.uk |
| Products Intro: |
|
|
| | ANTI-HOGG1 Basic information |
| Product Name: | ANTI-HOGG1 | | Synonyms: | ANTI-HOGG1;ANTI-OGG1 (HUMAN);ANTISERUM TO 8-OXOGUANINE-DNA GLYCOSYLASE;ANTI-8-OXOGUANINE DNA GLYCOSYLASE, HUMAN;POLYCLONAL ANTIBODY TO 8-OXOGUANINE-DNA GLYCOSYLASE (HUMAN), ANTI-OGG1;Anti-Mmh;Anti-OGG1 antibody produced in goat;Anti-8-oxoguanine DNA glycosylase | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HOGG1 Structure]() |
| | ANTI-HOGG1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-HOGG1 Usage And Synthesis |
| General Description | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. (provided by RefSeq) | | Biochem/physiol Actions | The gene OGG1 (8-oxoguanine DNA glycosylase) is responsible for the excision of 8-oxoguanine, which is the most common form of oxidative DNA damage and is removed by the base excision repair pathway. OGG1 also has lyase activity that results in a single strand break. Variation in OGG1 (8-oxoguanine DNA glycosylase) is associated with age-related cataract and serves as a genetic biomarker in indicating the same. |
| | ANTI-HOGG1 Preparation Products And Raw materials |
|