ChemicalBook > Product Catalog >API >Nervous system drugs >Sedative and hypnotic >Chloral hydrate

Chloral hydrate

Chloral hydrate Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +86 (0)571-855 867 18
Products Intro: Product Name:2,2,2-Trichloroethane-1,1-diol
Purity:98%(Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Chloral hydrate
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:302-17-0
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Shanghai Time Chemicals CO., Ltd.
Tel: +86-021-57951555
Products Intro: Product Name:Chloral hydrate
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Chloral hydrate

Lastest Price from Chloral hydrate manufacturers

  • Chloral hydrate
  • US $7.00 / kg
  • 2018-12-18
  • CAS:302-17-0
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100kg
Chloral hydrate Basic information
Product Name:Chloral hydrate
Synonyms:Amylofene;Aquachloral;Bi 3411;bi3411;Chloradorm;CHLORAL HYDRATE;'GROUND JOINT SEPARATION AID';1,1,1-trichloro-2,2-ethanediol
Product Categories:-;Miscellaneous;Organics;Method 551EPA;Method 8240;500 Series Drinking Water Methods;8000 Series Solidwaste Methods;EPA;Aldehydes;Bioactive Small Molecules;Building Blocks;C1 to C6;Carbonyl Compounds;C-CH;Cell Biology;Chemical Synthesis;Organic Building Blocks
Mol File:302-17-0.mol
Chloral hydrate Structure
Chloral hydrate Chemical Properties
Melting point 57 °C(lit.)
Boiling point 97 °C
density 1.43 g/mL at 20 °C
refractive index 1.4603 (estimate)
Fp 16 °C
storage temp. 0-6°C
solubility Very soluble in water, freely soluble in ethanol (96 per cent).
pka10(at 25℃)
Specific Gravity1.91
PH3.5-5.5 (20℃, 10%)
Water Solubility 660 g/100 mL
Merck 13,2080
BRN 1698497
Stability:Stable, but may be air or light sensitive. Incompatible with alcohols, cyanides, iodine, strong bases, carbonates.
CAS DataBase Reference302-17-0(CAS DataBase Reference)
NIST Chemistry ReferenceChloral hydrate(302-17-0)
EPA Substance Registry System1,1-Ethanediol, 2,2,2-trichloro-(302-17-0)
Safety Information
Hazard Codes T,F,Xn
Risk Statements 25-36/38-39/23/24/25-23/24/25-11-36/37/38-36-20/21/22
Safety Statements 26-45-25-23-36/37-16-27
RIDADR UN 3286 3/PG 2
WGK Germany 2
RTECS FM8750000
HazardClass 6.1(b)
PackingGroup III
HS Code 29055900
Hazardous Substances Data302-17-0(Hazardous Substances Data)
MSDS Information
SigmaAldrich English
ACROS English
Chloral hydrate Usage And Synthesis
Chemical Propertiescolourless crystals with a pentrating odour
Chemical PropertiesChloral is a combustible, oily liquid with a pungent irritating odor.
UsesTrichloroacetaldehyde Hydrate is a useful chemical reagent used as a sedative/hypnotic agent for the short-term treatment of insomnia. First developed in 1832, chloral hydrate is the oldest sleep medication still in use today. This medication is also used to calm you just before surgery or other procedures. It works by affecting certain parts of the brain to cause calmness.
Studies have shown that when used in pediatric sedation side effects such as hallucination, excessive sleep and seizures were observed. Drowsiness and trouble waking up in the morning, nausea, vomiting, stomach pain, diarrhea, and headache may occur. Stomach problems can be reduced by taking chloral hydrate with a full glass of water. It is sometimes administered to patients being treated with cyclophosphamide and it is known to inhibit some aldehyde dehydrogenases.
Besides, Chloral hydrate is a starting point for the synthesis of other organic compounds. It is the starting material for the production of chloral, which is produced by the distillation of a mixture of chloral hydrate and sulfuric acid, which serves as the desiccant.
DefinitionChEBI: An organochlorine compound that is the hydrate of trichloroacetaldehyde.
General DescriptionTransparent colorless crystals or white crystalline solid. Aromatic penetrating slightly acrid odor and a slightly bitter caustic taste. Alcoholic solution (1 in 20) does not at once redden moistened blue litmus paper.
Air & Water ReactionsWater soluble.
Reactivity ProfileChloral hydrate is incompatible with alkalis, alkaline earth metals, alkali carbonates and soluble barbiturates. Chloral hydrate is decomposed by sodium hydroxide. Chloral hydrate reduces ammoniacal silver nitrate. Chloral hydrate liquefies when triturated with an equal quantity of menthol, camphor or thymol. . Reaction of Chloral hydrate with hydroxylamine produces toxic hydrogen cyanide gas, Org. Synth., 1941, Vol. 1, 377.
HazardOverdose toxic, hypnotic drug, dangerous to eyes. Probable carcinogen.
Fire HazardFlash point data for Chloral hydrate are not available; however, Chloral hydrate is probably combustible.
Safety ProfileA human poison by ingestion and possibly other routes. Poison experimentally by ingestion, intravenous, and rectal routes. Moderately toxic by subcutaneous, parenteral, and intraperitoneal routes, Experimental reproductive effects. Human systemic effects by ingestion: general anesthetic, cardiac arrhythmias, blood pressure depression, eye effects, coma, pulse rate increase, arrhythmias. Human mutation data reported. Questionable carcinogen with experimental carcinogenic and tumorigenic data by skin contact. A sedative, anesthetic, and narcotic. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Cl-.
Potential ExposureChloral is used as an intermediate in the manufacture of such pesticides as DDT, methoxychlor, DDVP, naled, trichlorfon, and TCA. Chloral is also used in the production of chloral hydrate; used as a therapeutic agent with hypnotic, sedative, and narcotic effects; used in a time prior to the introduction of barbiturates
First aidMove victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim warm and quiet. Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed. Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.
ShippingUN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
IncompatibilitiesChloral hydrate reacts with strong bases forming chloroform. Contact with acids, or exposure to light may cause polymerization. Reacts with water, forming chloral hydrate. Reacts with oxidizers, with a risk of fire or explosions.
Waste DisposalIncineration after mixing with another combustible fuel; care must be taken to assure complete combustion to prevent phosgene formation; an acid scrubber is necessary to remove the halo acids produced.
Tag:Chloral hydrate(302-17-0) Related Product Information
Poly(ethylene glycol) Ferric chloride hexahydrate hydrazine hydrate Citric acid monohydrate Ethylene glycol diacetate Chloroacetaldehyde Trichloroisocyanuric acid Trichloroethylene Chloroform 2-Butoxyethanol Ethylene glycol hydrate Trichlorosilane Chloral hydrate 2-Butoxyethyl acetate MELIBIOSE Sucralose 2-Ethoxyethanol