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Candesartan

Candesartan Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: Abel@chembj.com
Products Intro: Product Name:Candesartan
CAS:139481-59-7
Purity:99% Package:2750/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Candesartan
CAS:139481-59-7
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:139481-59-7
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:Candesartan
CAS:139481-59-7
Company Name: PI & PI BIOTECH INC.
Tel: 020-81716320
Email: Sales@pipitech.com
Products Intro: Product Name:Candesartan (Candesartan Cilexetil impurity G)
CAS:139481-59-7
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com Remarks:2-ethoxy-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid (candesartan)

Lastest Price from Candesartan manufacturers

  • Candesartan
  • US $1.00 / KG
  • 2019-05-13
  • CAS:139481-59-7
  • Min. Order: 1KG
  • Purity: 40%-99%
  • Supply Ability: 1000kg
Candesartan Basic information
Product Name:Candesartan
Synonyms:2-ETHOXY-1-[[2'-(1H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL]METHYL]-1H-BENZIMIDAZOLE-7-CARBOXYLIC ACID;CANDESARTAN;CV-11974;CILEXITIL;Candesartan[CandesartanCilexetilIntermediates];Candesartan ( For Candesartan Cilexetil );2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid, CV-11974;2-Ethoxy-1-[2'-(1-triphenylmethyltetrazol-5-yl)-biphenyl-4-yl-methyl]benzimidazole-7-carboxylicacidcyclohexyl-1-chloroethylcarbonate
CAS:139481-59-7
MF:C24H20N6O3
MW:440.45
EINECS:604-138-8
Product Categories:-;Active Pharmaceutical Ingredients;Candesartan Cilexetil;API intermediates;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Candesartan Cilexatil;Aromatics;Heterocycles;Pharmaceutical raw material;Isotope
Mol File:139481-59-7.mol
Candesartan Structure
Candesartan Chemical Properties
Melting point 183-185°C
RTECS DD6671000
storage temp. -20°C Freezer
Water Solubility Soluble in ethyl acetate, methanol, water (<1 mg/ml at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C).
CAS DataBase Reference139481-59-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36-60-36/37-9
HS Code 29419000
Hazardous Substances Data139481-59-7(Hazardous Substances Data)
Candesartan Usage And Synthesis
Chemical PropertiesCrystalline Solid
UsesAn angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive
Usesantihypertensive, angiotensin II inhibitor
DefinitionChEBI: A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin eceptor antagonist used for the treatment of hypertension.
Brand nameAtacand (AstraZeneca).
General DescriptionCandesartan, (+)-1-[[(cyclohexyloxy)carbonyl]-oxy]ethyl 2- ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate(Atacand), like losartan, possesses the acidic tetrazole system,which most likely plays a role in binding to the angiotensin IIreceptor similarly to the acidic groups of angiotensin II. Also,the imidazole system has been replaced with a benzimidazolepossessing an ester at position. This ester must be hydrolyzedto the free acid. Fortunately, this conversion takesplace fairly easily because of the carbonate in the ester sidechain. This facilitates hydrolysis of the ester so much thatconversion to the free acid takes place during absorption fromthe gastrointestinal tract.
Candesartan Preparation Products And Raw materials
Raw materialsThionyl chloride-->Potassium carbonate-->Trifluoroacetic acid-->tert-Butanol-->Sodium azide-->Benzyl bromide-->Mineral oil-->3-Nitrophthalic acid
Tag:Candesartan(139481-59-7) Related Product Information
Telmisartan Irbesartan Valsartan Metformin Ethyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Methyl]Benzimidazole]-7-Carboxylate TRITYL CANDESARTAN CILETEXITIL,TRITYL CANDESARTAN CILEXETIL CANDERSARTAN CILEXETIL [3H(G)] Candesartan PHENYL VALERATE CANDESARTAN CILEXETIL,CANDESARTAN CILEXITIL DIETHOXYMETHANE Methyl bromide Kresoxim-methyl Ethoxyquin Ethoxy 2-[[[[(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzoic acid methyl ester Methyl salicylate 4-Ethoxyphenol