N-DESMETHYL IMATINIB manufacturers
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| | N-DESMETHYL IMATINIB Basic information |
| Product Name: | N-DESMETHYL IMATINIB | | Synonyms: | N-DESMETHYL GLEEVEC;N-DESMETHYL IMATINIB;Imatinib desmethyl (as formate);Imatinib Impurity 53;N-DESMETHYL IMATINIB USP/EP/BP;Benzamide, N-[2-methyl-5-[[4-[(4-methyl-1-piperazinyl)methyl]benzoyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]-N-[4-(3-pyridinyl)-2-pyrimidinyl]-;N-DESMETHYL IMATINIB impurity B;N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde | | CAS: | 1356565-46-2 | | MF: | C42H47N9O2 | | MW: | 709.88 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | N-DESMETHYL IMATINIB Chemical Properties |
| Melting point | 180 - 190°C | | density | 1.248±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | pka | 13.20±0.70(Predicted) | | form | Solid | | color | Off-White to Light Yellow |
| | N-DESMETHYL IMATINIB Usage And Synthesis |
| Uses | Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde is an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). | | Uses | N-Desmethyl Imatinib (Imatinib EP Impurity C) is a metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product. |
| | N-DESMETHYL IMATINIB Preparation Products And Raw materials |
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