尿苷5'-三磷酸酯
| 中文名称 | 尿苷5'-三磷酸酯 |
|---|---|
| 中文同义词 | UTP【尿苷三磷酸】;尿苷三磷酸;尿苷-5'-三磷酸;尿苷-5-三磷酸钠盐;尿苷5'-三磷酸酯;尿苷-5′-三磷酸酯 三钠盐 溶液;地夸磷索杂质B;三磷酸尿酐二钠(UTP) |
| 英文名称 | UTP |
| 英文同义词 | 5'-URIDYLATE TRIPHOSPHATE;UTP, 3NA;UTP, NA3H;UTP SODIUM SALT;URIDINE-5'-TRIPHOSPHATE NA3-SALT;URIDINE-5'-TRIPHOSPHATE SODIUM;URIDINE 5'-TRIPHOSPHATE SODIUM SALT;URIDINE 5-TRIPHOSPHATE TRISODIUM |
| CAS号 | 63-39-8 |
| 分子式 | C9H15N2O15P3 |
| 分子量 | 484.14 |
| EINECS号 | 200-558-7 |
| 相关类别 | 对照品-杂质对照品;NTP |
| Mol文件 | 63-39-8.mol |
| 结构式 |  |
尿苷5'-三磷酸酯 性质
| 密度 | 2.106±0.06 g/cm3(Predicted) |
|---|---|
| 闪点 | 113 °C |
| 储存条件 | Sealed in dry,2-8°C |
| 溶解度 | Easily soluble (water) |
| 形态 | 液体 |
| 酸度系数(pKa) | pK1:7.58 (25°C) |
| 颜色 | 无色 |
| PH值 | 7.0 ± 0.1 |
| 生物来源 | yeast (Candida Utilis) |
| 水溶解性 | Water : ≥ 150 mg/mL (309.83 mM) |
| InChIKey | PGAVKCOVUIYSFO-XVFCMESISA-N |
| SMILES | C(OP(=O)(O)OP(O)(=O)OP(O)(O)=O)[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1O |
| CAS 数据库 | 63-39-8(CAS DataBase Reference) |
| EPA化学物质信息 | Uridine 5'-(tetrahydrogen triphosphate) (63-39-8) |
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Human Endogenous Metabolite
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Uridine triphosphate treatment induces Schwannoma cell migration through activation of P2Y2 receptors and through the increase of extracellular matrix metalloproteinase-2 (MMP-2) activation and expression. Uridine triphosphate-induced proliferation is mediated by protein kinase D, Src-family tyrosine kinase, Ca/calmodulin-dependent protein kinase II, phosphatidylinositol 3-kinase (PI3K), Akt, and phospholipase D. Uridine triphosphate increases phosphorylation of Akt through protein kinase C, Src-family tyrosine kinase, Ca/calmodulin-dependent protein kinase II, and PI3K.
Uridine triphosphate reduces mitochondrial calcium levels following hypoxia. Early or late uridine triphosphate preconditioning is effective to reduce infarct size and superior myocardial function. Uridine triphosphate treatment increases the number of monocytes and macrophages infiltrating the pouch and up-regulates the gene expression of IL-4 and IL-13 in the regional lymph nodes.
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 20/21/22-68/20/21/22 |
| 安全说明 | 22-26-36 |
| WGK Germany | 1 |
| 提供商 | 语言 |
|---|---|
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英文
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