| 中文名称 | (4R,4aβ,7aα,11aβ,14aα)-4β,11β-Dihydroxy-6aα,13aα-di(methylthio)-4,4a,6a,7,11,11a,14,14a-octahydro-1H,6H-pyrazino[1,2-a:4,5-a']diindole-1,6,8,13(7aH,13aH)-tetrone |
|---|---|
| 中文同义词 | |
| 英文名称 | (4R,4aβ,7aα,11aβ,14aα)-4β,11β-Dihydroxy-6aα,13aα-di(methylthio)-4,4a,6a,7,11,11a,14,14a-octahydro-1H,6H-pyrazino[1,2-a:4,5-a']diindole-1,6,8,13(7aH,13aH)-tetrone |
| 英文同义词 | (4R,4aβ,7aα,11aβ,14aα)-4β,11β-Dihydroxy-6aα,13aα-di(methylthio)-4,4a,6a,7,11,11a,14,14a-octahydro-1H,6H-pyrazino[1,2-a:4,5-a']diindole-1,6,8,13(7aH,13aH)-tetrone;Exserohilone;PubChem ID: 188607;1H,6H-Pyrazino[1,2-a:4,5-a']diindole-1,6,8,13(4H,6aH)-tetrone, 4a,7,7a,11,11a,13a,14,14a-octahydro-4,11-dihydroxy-6a,13a-bis(methylthio)-, (4R,4aR,6aS,7aR,11R,11aR,13aS,14aR)-rel-(-)- (9CI) |
| CAS号 | 99572-22-2 |
| 分子式 | C20H22N2O6S2 |
| 分子量 | 450.52 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 99572-22-2.mol |
| 结构式 | ![(4R,4aβ,7aα,11aβ,14aα)-4β,11β-Dihydroxy-6aα,13aα-di(methylthio)-4,4a,6a,7,11,11a,14,14a-octahydro-1H,6H-pyrazino[1,2-a:4,5-a']diindole-1,6,8,13(7aH,13aH)-tetrone 结构式](CAS/20210111/GIF/99572-22-2.gif) |
(4R,4aβ,7aα,11aβ,14aα)-4β,11β-Dihydroxy-6aα,13aα-di(methylthio)-4,4a,6a,7,11,11a,14,14a-octahydro-1H,6H-pyrazino[1,2-a:4,5-a']diindole-1,6,8,13(7aH,13aH)-tetrone 性质
| 沸点 | 812.6±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.62±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 11.81±0.70(Predicted) |
(4R,4aβ,7aα,11aβ,14aα)-4β,11β-Dihydroxy-6aα,13aα-di(methylthio)-4,4a,6a,7,11,11a,14,14a-octahydro-1H,6H-pyrazino[1,2-a:4,5-a']diindole-1,6,8,13(7aH,13aH)-tetrone 用途与合成方法
Exserohilone ((-)-Exserohilone) 是一种硫代二酮哌嗪衍生物，可抑制 TNF-α 诱导的 ROS 生成和 MMP-1 分泌。Exserohilone 增加人真皮成纤维细胞中 I 型前胶原 α1 的分泌。