| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Δ2-CefepiMe Etherate Dihydrochloride Salt
CAS:88040-25-9
Package:2.5Mg,25Mg
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Δ2-Cefepime
CAS:88040-25-9
Purity:>95%
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| | Δ2-Cefepime Basic information |
| Product Name: | Δ2-Cefepime | | Synonyms: | Δ2-Cefepime;Δ2-CefepiMe Etherate;1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-en-3-yl]Methyl]-1-MethylpyrrolidiniuM Inner Salt Etherate;Δ2-CefepiMe Etherate Dihydrochloride Salt;(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate,ethoxyethane;Cefepime Δ - 3 Isomer;Δ2-Cefepime;Cefepime Δ - 3 Isomer | | CAS: | 88040-25-9 | | MF: | C23H34N6O6S2 | | MW: | 554.68266 | | EINECS: | | | Product Categories: | Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds | | Mol File: | 88040-25-9.mol |  |
| | Δ2-Cefepime Chemical Properties |
| Melting point | >151°C (dec.) | | storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere | | solubility | Water (Slightly) | | form | Solid | | color | White to Off-White | | InChIKey | DBCVQAGQPYVVDA-XVKMNWMGSA-N |
| | Δ2-Cefepime Usage And Synthesis |
| Uses | Δ2-Cefepime is the Δ2-isomer of Cefepime (C242750), a new series of cephalosporins. | | Uses | The Δ2-isomer of Cefepime (C242750), a new series of cephalosporins. | | Preparation | First, cefepime and N-trimethylsilylacetamide were added to dichloromethane for 0.5 h. Subsequently, triethylamine dissolved in dichloromethane was added to the reaction system between 2-5 °C. Adjust the temperature to 2-5 °C and react for 24 h. After adding water, the aqueous layer was separated, and the aqueous phase was washed with methylene chloride. Wait for the solution to cool to 2-5 °C and adjust the pH=3 with sulfuric acid. Stir the resulting slurry for 2h. Filter to collect the solids and wash with water, adjust the pH=7.5-8.0 with sodium bicarbonate aqueous solution, add carbon, and stir for 30 min. Filter the mixture to collect the filtrate and adjust pH=3 with sulfuric acid. Finally, the solids are filtered and collected, and product Δ2-Cefepime is obtained by washing and drying.
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| | Δ2-Cefepime Preparation Products And Raw materials |
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