- XL147
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- $2.00 / 1kg
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2019-07-06
- CAS:956958-53-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
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| | XL147 Chemical Properties |
| Boiling point | 638.9±65.0 °C(Predicted) | | density | 1.538 | | storage temp. | Store at -20°C | | solubility | ≥22.45 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH | | form | solid | | pka | 6.71±0.30(Predicted) |
| | XL147 Usage And Synthesis |
| Description | XL147 analog is an analog of XL147 . | | Uses | XL147 analogue is one of Pyrimidine derivatives as JAK-2 inhibitors in combination with other agents and their use in the treatment of diseases. | | Definition | ChEBI: XL147 is a sulfonamide that is the N-4-toluenesulfonyl (N-tosyl) derivative of N-(2,1,3-benzothiadiazol-5-yl)quinoxaline-2,3-diamine. A selective PI3K inhibitor used in cancer treatment. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and an antineoplastic agent. It is a sulfonamide, a quinoxaline derivative, a benzothiadiazole and an aromatic amine. | | target | PI3Kα |
| | XL147 Preparation Products And Raw materials |
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