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CCT129202

CCT129202 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:CCT-129202
CAS:942947-93-5
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:CCT129202
CAS:942947-93-5
Purity:0.99 Package:5KG;1KG
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:cct 129202
CAS:942947-93-5
Purity:0.99 Package:1kg
Company Name: career henan chemical co
Tel: +86-0371-86658258 15093356674;
Email: factory@coreychem.com
Products Intro: Product Name:CCT129202
CAS:942947-93-5
Purity:99% Package:1g;1USD
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:CCT129202
CAS:942947-93-5
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer

CCT129202 manufacturers

  • CCT129202
  • CCT129202 pictures
  • $1.00 / 1g
  • 2020-01-09
  • CAS:942947-93-5
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 200kg
CCT129202 Basic information
Product Name:CCT129202
Synonyms:CCT129202;2-[4-[6-Chloro-2-(4-dimethylaminophenyl)-3H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]-N-(thiazol-2-yl)acetamide;2-(4-(6-Chloro-2-(4-(dimethylamino)phenyl)-1H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)-N-(th;CCT129202 (CCT-129202;CS-407;CCT129202 USP/EP/BP;1-Piperazineacetamide, 4-[6-chloro-2-[4-(dimethylamino)phenyl]-3H-imidazo[4,5-b]pyridin-7-yl]-N-2-thiazolyl-
CAS:942947-93-5
MF:C23H25ClN8OS
MW:497.02
EINECS:
Product Categories:Inhibitor;Inhibitors
Mol File:942947-93-5.mol
CCT129202 Structure
CCT129202 Chemical Properties
density 1.427
storage temp. Store at -20°C
solubility DMSO : 1 mg/mL (2.01 mM; Need ultrasonic)
form Powder
pka9.26±0.50(Predicted)
Safety Information
MSDS Information
CCT129202 Usage And Synthesis
Biological ActivityCCT129202 is an ATP-competitive pan-Aurora inhibitor with IC50s of 0.042 μM, 0.198 μM and 0.227 μM for Aurora A, Aurora B and Aurora C, respectively, and has a weaker effect on FGFR3, GSK3β, PDGFRβ, etc.
in vivoCCT129202 at a dose of 100 mg/kg subcutaneously injected HCT116 colon xenografts in athymic mice, after 30 minutes, caused a ~50% decrease in histone H3 phosphorylation, and after 9 days of treatment, significantly inhibited tumor growth, compared with the control group , inhibited by 57.7%.
targetAurora A
CCT129202 Preparation Products And Raw materials
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