| Company Name: |
Santa Cruz Biotechnology Inc
|
| Tel: |
021-60936350 |
| Email: |
scbt@scbt.com |
| Products Intro: |
Product Name:9,11-methane-epoxy Prostaglandin 1α
CAS:72517-81-8
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| Company Name: |
Absin Bioscience Inc.
|
| Tel: |
021-38015121-8802 |
| Email: |
chenjw@absin.cn |
| Products Intro: |
CAS:72517-81-8
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:9,11-methane-epoxy Prostaglandin F1α
CAS:72517-81-8
Package:>96% Remarks:10007850
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| | 9,11-methane-epoxy Prostaglandin F1α Basic information |
| Product Name: | 9,11-methane-epoxy Prostaglandin F1α | | Synonyms: | 9,11-methane-epoxy Prostaglandin F1α;9,11-methane-epoxy
Prostaglandin 1α;VGRVXLWYKKBTNM-KQMLLPOFSA-N;9,11-methane-epoxy Prostaglandin F1.alpha.;9,11-methane-epoxy Prostaglandin 1alpha;2-Oxabicyclo[2.2.1]heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-, [1α,4α,5β,6α(1E,3S*)]- (9CI);9,11-methane-epoxy Prostaglandin 1α | | CAS: | 72517-81-8 | | MF: | C21H36O4 | | MW: | 352.51 | | EINECS: | | | Product Categories: | | | Mol File: | 72517-81-8.mol |  |
| | 9,11-methane-epoxy Prostaglandin F1α Chemical Properties |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 1 mg/ml |
| | 9,11-methane-epoxy Prostaglandin F1α Usage And Synthesis |
| Description | Prostaglandin (PG) endoperoxides are intermediates in the biosynthesis of PGs, thromboxanes, and prostacyclin. The endoperoxides, PGH2 and PGG2, induce rapid and irreversible aggregation of human platelets.1 PGH1 and PGG1 are known to contract smooth muscle preparations, but are lacking in aggregatory effects. 9,11-methane-epoxy Prostaglandin F1α (9,11-methane-epoxy PGF1α) is a stable epoxymethano analog of PGH1 that produces a strong and dose-related aggregation of washed rabbit platelets (EC50 = 0.88 μM) and contraction of rabbit aortic strips (EC50 = 0.11 μM).1 9,11-methane-epoxy PGF1α induces contraction of guinea pig tracheas (EC50 = 3.4 μM) with a maximal contraction of about 60% of that caused by a submaximal dose of histamine. | | References | 1. Morita, A., Nishino, H., Hasegawa, K., et al. Biological activities of prostaglandin H1 analogs Prostaglandins 18(4),529-540(1979). |
| | 9,11-methane-epoxy Prostaglandin F1α Preparation Products And Raw materials |
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