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| tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Basic information |
Product Name: | tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate | Synonyms: | tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate;tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate-10;6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate;2-Methyl-2-propanyl 6-cyano-2-[2-(4-ethyl-3-iodophenyl)-2-propany l]-1H-indole-3-carboxylate;6-Cyano-2-[1-(4-ethyl-3-iodophenyl)-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester;Alectinib Impurity 6;TERT-BUTYL 6-CYANO-2- (2-(4-ETHYL-3-IODOPHENYL)PROPAN-2-YL) -1H-INDOLE-3-CARBOXYLATE _ 1256584-75-4;tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate/tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate | CAS: | 1256584-75-4 | MF: | C25H27IN2O2 | MW: | 514.4 | EINECS: | | Product Categories: | 1256584-75-4 | Mol File: | 1256584-75-4.mol | |
| tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Chemical Properties |
Boiling point | 609.3±55.0 °C(Predicted) | density | 1.43±0.1 g/cm3(Predicted) | pka | 14.00±0.30(Predicted) | InChI | InChI=1S/C25H27IN2O2/c1-7-16-9-10-17(13-19(16)26)25(5,6)22-21(23(29)30-24(2,3)4)18-11-8-15(14-27)12-20(18)28-22/h8-13,28H,7H2,1-6H3 | InChIKey | QJJFMODIDDQXRV-UHFFFAOYSA-N | SMILES | N1C2=C(C=CC(C#N)=C2)C(C(OC(C)(C)C)=O)=C1C(C1=CC=C(CC)C(I)=C1)(C)C |
| tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Usage And Synthesis |
Uses | tert-?Butyl 6-?Cyano-?2-?(2-?(4-?ethyl-?3-?iodophenyl)?propan-?2-?yl)?-?1H-?indole-?3-?carboxylate is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. |
| tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Preparation Products And Raw materials |
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