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2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl-

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2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:AZ-4217；AZ 4217;AZ4217
CAS:1383846-83-0
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:AZ-4217
CAS:1383846-83-0
Purity:98% Package:5 mg
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:AZ-4217
CAS:1383846-83-0
Purity:98%+ HPLC Package:10mg，500mg，1g，2g，5g，10g，More
2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl- Basic information
Product Name:2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl-
Synonyms:2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl-;5-[(1R)-3-amino-4-fluoro-1-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]isoindol-1-yl]-1-ethyl-3-methylpyridin-2-one;AZ-4217 (AZ4217)
CAS:1383846-83-0
MF:C30H25FN4O
MW:476.54
EINECS:
Product Categories:
Mol File:1383846-83-0.mol
2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl- Structure
2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl- Chemical Properties
Boiling point 732.5±70.0 °C(Predicted)
density 1.21±0.1 g/cm3(Predicted)
pka3.72±0.40(Predicted)
Safety Information
MSDS Information
2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl- Usage And Synthesis
DescriptionAZ-4217 is a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. AZ-4217 has IC50 160 pM in human SH-SY5Y cells with an excellent in vivo efficacy. AZ-4217 may have potential for treatment of AD. BACE1 inhibition thus addresses a key mechanism in AD and its potential as a therapeutic target is currently being addressed in clinical studies.
2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl- Preparation Products And Raw materials
Tag:2(1H)-Pyridinone, 5-[(1R)-3-aMino-4-fluoro-1-[3-[5-(1-propyn-1-yl)-3-pyridinyl]phenyl]-1H-isoindol-1-yl]-1-ethyl-3-Methyl-(1383846-83-0) Related Product Information