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J & K SCIENTIFIC LTD.
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Product Name:Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride
CAS:55266-18-7
Package:1g,500Mg
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| | Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride Basic information |
| Product Name: | Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride | | Synonyms: | Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride;Manganese(III) meso-tetra(4-carboxyphenyl)porphine chloride;Mn(III)TBAP (chloride);5,10,15,20-Tetrakis(4-carboxyphenyl)porphyrin-Mn(III) chloride (MnTBAP);5,10,15,20-Tetrakis(4-carboxyphenyl)-21H,23H-porphine]manganese(III) chloride | | CAS: | 55266-18-7 | | MF: | C48H28ClMnN4O8 | | MW: | 879.148969 | | EINECS: | | | Product Categories: | | | Mol File: | 55266-18-7.mol |  |
| | Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride Chemical Properties |
| storage temp. | -20C | | solubility | Soluble in 0.1M NaOH | | form | Brown solid | | color | Black | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in 0.1M NaOH may be stored at -20° for up to 1 month. |
| | Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride Usage And Synthesis |
| Description | MnTBAP (55266-18-7) is a superoxide dismutase (SOD) mimetic. Potent peroxynitrite scavenger but does not scavenge nitric oxide. | | Uses | MnTBAP chloride is a cell permeable superoxide dismutase mimetic and peroxynitrite scavenger. | | General Description | Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50 ~40 μM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 (Cat. No. 309825) by peroxynitrite, but does not scavenge nitric oxide (NO). | | Biochem/physiol Actions | Cell permeable: yes | | References | 1) Szabo et al. (1996), Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial resporation in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger; FEBS Lett., 381 82
2) Faulkner et al. (1994), Stable MN(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo; J. Biol. Chem., 269 23471 |
| | Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride Preparation Products And Raw materials |
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