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3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid

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3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Suppliers list
Company Name: China National Standard Pharmaceutical Corporation Limited
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Products Intro: Product Name:Eltrombopag Impurity 42
CAS:376591-99-0
Purity:0.95 Package:Vials
Company Name: Shanghai YuLue Chemical Co., Ltd.  
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Products Intro: CAS:376591-99-0
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Products Intro: Product Name:Eltrombopag Impurity 42
CAS:376591-99-0
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
CAS:376591-99-0
Purity:95+% Package:100mg;250mg;500mg;1g;2.5g;5g;10g
Company Name: Hubei Xinyang Medical Technology Co., Ltd  
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Products Intro: Product Name:Eltrombopag Impurity 42
CAS:376591-99-0
Purity:99% Package:10mg;50mg;100mg
3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Basic information
Product Name:3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Synonyms:3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid;3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid;[1,1'-Biphenyl]-3-carboxylic acid, 3'-[2-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-;Eltrombopag Impurity 46(Mixture of Z/E-Isomers)
CAS:376591-99-0
MF:C25H22N4O4
MW:442.47
EINECS:
Product Categories:
Mol File:376591-99-0.mol
3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Structure
3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Chemical Properties
Boiling point 656.8±65.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
pka-1.26±0.40(Predicted)
Safety Information
MSDS Information
3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Usage And Synthesis
DefinitionChEBI: Eltrombopag is a hydrazine in which each nitrogen atom is substituted, one by a 3'-carboxy-2-hydroxy[1,1'-biphenyl]-3-yl group and the other by a 1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene group. A small molecule agonist of the c-mpl (TpoR) receptor (the physiological target of the hormone thrombopoietin), it has been developed as a medication for conditions that lead to thrombocytopenia (abnormally low platelet counts). It has a role as a thrombopoietin receptor agonist and a xenobiotic. It is a member of hydrazines, a member of pyrazoles and a member of benzoic acids.
3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Preparation Products And Raw materials
Raw materials2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one-->3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID-->3'-aMino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid hydrochloride-->1-(3,4-DIMETHYLPHENYL)-3-METHYL-3-PYRAZOLIN-5-ONE
Tag:3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid(376591-99-0) Related Product Information