- Nile Red
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- $0.00 / 1g
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2026-04-30
- CAS:7385-67-3
- Min. Order: 1g
- Purity: 95%
- Supply Ability: 1kg/month
- Nile Red
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- $41.00 / 25mg
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2026-04-21
- CAS:7385-67-3
- Min. Order:
- Purity: 98.44%
- Supply Ability: 10g
- NILE RED
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- $30.00 / 1KG
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2025-06-27
- CAS:7385-67-3
- Min. Order: 50KG
- Purity: 99%
- Supply Ability: 500000kg
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| | Nile Red Basic information |
| Product Name: | Nile Red | | Synonyms: | NILE RED;9-(diethylamino)-5h-benzo[a]phenoxazin-5-on;nile;9-(diethylamino)benzo[a]phenoxazin-5(5H)-one;FLUORESCENCE QY-STANDARD E CERTIFIED;9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on;Nile Red, pure, 99%;9-Diethylamino-benzo[a]phenoxazin-5-one | | CAS: | 7385-67-3 | | MF: | C20H18N2O2 | | MW: | 318.37 | | EINECS: | 230-966-0 | | Product Categories: | marker;Electroluminescence;Functional Materials | | Mol File: | 7385-67-3.mol |  |
| | Nile Red Chemical Properties |
| Melting point | 203-205 °C(lit.) | | Boiling point | 457.53°C (rough estimate) | | density | 1.1871 (rough estimate) | | refractive index | 1.5700 (estimate) | | storage temp. | 2-8°C | | solubility | methanol: soluble1mg/mL | | pka | 4.08±0.20(Predicted) | | form | Powder | | color | Dark red to maroon | | Appearance | Green to Dark Green Solid | | λmax | 553 nm | | BRN | 279110 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChI | InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3 | | InChIKey | VOFUROIFQGPCGE-UHFFFAOYSA-N | | SMILES | C12=CC=CC=C1C(=O)C=C1C2=NC2=C(C=C(N(CC)CC)C=C2)O1 | | CAS DataBase Reference | 7385-67-3(CAS DataBase Reference) | | EPA Substance Registry System | 5H-Benzo[a]phenoxazin-5-one, 9-(diethylamino)- (7385-67-3) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | F | 8-10 | | TSCA | TSCA listed | | HS Code | 29349990 | | Storage Class | 11 - Combustible Solids |
| | Nile Red Usage And Synthesis |
| Description | Nile Red is an aphotostable and lipophilic stain for intracellular lipids and hydrophobic domains of proteins and also for staining of lysosomal phospholipid inclusions. | | Uses | Nile red is a lipophilic stain. It stains intracellular lipid droplets. Nile red is also intensely fluorescent, with a strong yellow-gold emission if included into a lipid-rich environment.
 | | Definition | Nile Red is an organic heterotetracyclic compound that is 5H-benzo[a]phenoxazin-5-one substituted at position 9 by a diethylamino group. | | Application | Used as a polarity-sensitive fluorescent probe of lipids and proteins. | | General Description | Nile Red is an uncharged hydrophobic molecule and a benzophenoxazone dye. It functions as a fluorescent probe for intracellular lipids and hydrophobic domains of proteins. This dye is fluorescent in all organic solvents. Its fluorescence colors range from golden yellow to deep red. | | Synthesis | Using the 1,3-Naphthalenediol Approach to synthsis Nile red. To a solution of 1,3-naphthalenediol (0.50 g, 3.12 mmol) in anhydrous DMF (25 mL) was added 4-nitroso-N,N-diethylaniline (0.56 g, 3.12 mmol). This reaction mixture was stirred at 80 °C (DrySyn heating block) for 16 h and concentrated under reduced pressure. The crude product was purified by flash chromatography (050% EtOAc in hexanes) to obtain Nile Red, which crystallized from hexanes in green crystals (0.80 g, 2.50 mmol). Yield: 80%[1].
| | storage | Room temperature | | References | [1] Mick Hornum*. “Substituted 9-Diethylaminobenzo[a]phenoxazin-5-ones (Nile Red Analogues): Synthesis and Photophysical Properties.” The Journal of Organic Chemistry 86 2 (2020): 1471–1488.
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| | Nile Red Preparation Products And Raw materials |
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