| Company Name: |
Atlas antibodies
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| Tel: |
46-854595850 |
| Email: |
order@atlasantibodies.com |
| Products Intro: |
Product Name:Anti-DSE
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Anti-DSE antibody produced in rabbit
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| Company Name: |
Neobioscience Co., Ltd.
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| Tel: |
4006-800-892 |
| Email: |
info@neobioscience.com |
| Products Intro: |
Product Name:Anti-DSE
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:clone 6D4, purified immunoglobulin, buffered aqueous solution
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| | Anti-Squamous cell carcinoma antigen recognized by T-cells 2 Basic information |
| Product Name: | Anti-Squamous cell carcinoma antigen recognized by T-cells 2 | | Synonyms: | Anti-DSE antibody produced in rabbit;Anti-SART2 antibody produced in rabbit;Monoclonal Anti-SART2 antibody produced in mouse;Anti-Chondroitin-glucuronate 5-epimerase;Anti-Dermatan-sulfate epimerase precursor;Anti-DS epimerase;Anti-DSE;Anti-SART-2 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-Squamous cell carcinoma antigen recognized by T-cells 2 Structure]() |
| | Anti-Squamous cell carcinoma antigen recognized by T-cells 2 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| | Anti-Squamous cell carcinoma antigen recognized by T-cells 2 Usage And Synthesis |
| Biological Activity | DSE (dermatan sulfate epimerase) is responsible for the epimerization of GlcUA (glucuronic acid) into IdoUA (iduronic acid) in chondroitin chains, and the conversion of IdoUA into GlcUA in dermatans. Mutation in this gene is associated with musculocontractural Ehlers-Danlos syndromes (MCEDS), which is an outcome of abnormalities in dermatan sulfate (DS) synthesis. It is up-regulated in squamous cell carcinomas, and has three different N-glycosylated isoforms. It is also overexpressed in esophagus squamous cell carcinoma (ESCC), and its inactivation leads to reduced IdaUA levels, leading to decreased tumor migration and invasiveness. It is expressed in glioma, gynecological cancer, pancreatic cancer, colorectal carcinoma, and prostate cancer. Its expression is not seen in breast cancer cells. |
| | Anti-Squamous cell carcinoma antigen recognized by T-cells 2 Preparation Products And Raw materials |
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