- Choline bicarbonate
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- $8.00 / 1kg
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2024-04-22
- CAS:78-73-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- Choline bicarbonate
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- $15.00 / 1KG
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2021-08-12
- CAS:78-73-9
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Choline bicarbonate
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- $6.60 / 1KG
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2019-12-26
- CAS:78-73-9
- Min. Order: 1KG
- Purity: 97%-99%
- Supply Ability: 1kg-1000kg
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| | Choline bicarbonate Basic information |
| Product Name: | Choline bicarbonate | | Synonyms: | HYDROXYETHYLTRIMETHYLAMMONIUM BICARBONATE;CHOLINE BICARBONATE;CHOLINE BICARBONATE SALT;CHOLINE HYDROGEN CARBONATE;(2-HYDROXYETHYL)TRIMETHYLAMMONIUM BICARBONATE;[2-HYDROXYETHYL]TRIMETHYLAMMONIUM BICARBONATE SALT;2-hydroxy-n,n,n-trimethyl-ethanaminiucarbonate(1:1)(salt);Choline bicarbonate dibenzenesulfonimide salt | | CAS: | 78-73-9 | | MF: | C6H15NO4 | | MW: | 165.19 | | EINECS: | 201-137-0 | | Product Categories: | | | Mol File: | 78-73-9.mol |  |
| | Choline bicarbonate Chemical Properties |
| density | 1.17 g/mL at 25 °C (lit.) | | vapor pressure | 23.904hPa at 25℃ | | refractive index | n20/D 1.45 | | storage temp. | 2-8°C | | solubility | Methanol (Sparingly), Water (Soluble) | | form | Colourless Solution | | Water Solubility | 750g/L at 20℃ | | InChIKey | DQKGOGJIOHUEGK-UHFFFAOYSA-M | | CAS DataBase Reference | 78-73-9(CAS DataBase Reference) | | EPA Substance Registry System | Choline carbonate (1:1) (78-73-9) |
| | Choline bicarbonate Usage And Synthesis |
| Chemical Properties | Colorless liquid.Miscible with water. | | Uses | Choline, a water soluble essential nutrient, is used by the body to make phosphatidylcholine phosphatides and neurotransmitter such as acetylcholine. Choline is used to study a wide range of biological processes from stem cell development to neurological disease studies. Also, An alkaline intermediate useful for preparing salts. | | Uses | Choline Bicarbonate is compound is used for protein delivery, Alkaline catalyst, intermediate for choline salts and surfactants. | | Reactions | [1CA:3PE] - (1:2) Choline 3-Pentenoate Synthesis
![Chemical reactions in the synthesis of [1CA:3PE].](/NewsImg/2024-04-22/6384939942527863577745004.png "Chemical reactions in the synthesis of [1CA:3PE].")
An oil bath was heated to approximately 60°C and the stirrer on the hot plate was adjusted to 410 RPM. 3.5022g of 3-Pentenoic acid (MW: 100.12g/mol) were weighed and placed in a 500 mL RBF. 3.6254g of Choline Bicarbonate (MW: 165.19g/mol) were weighed and added to the RBF in a drop-wise manner using a glass Pasteur pipette. Less than 1 mL of milli-Q water was used to rinse the master pipette and weighing materials, the milli-Q was then added to the RBF. The mixture was left stirring on heat overnight for approximately 24 hours. The mixture was then placed on the rotary-evaporator and set to 15 mbar for just over 1 hour in order to evaporate any remaining solvents. The mass of the final product was weighed and noted; 4.5891g of [1CA:3PE] were obtained. The solution was then placed in the vacuum oven set at 60°C for over 48 hours with the top left off. Time sensitivity during this step was not as imperative as other steps since the purpose of this step was to dry out any remaining solvents or water in the IL. Once removed from the vacuum oven, the solution was reweighed and an NMR was obtained for characterization purposes. The final mass of [1CA:3PE] being 4.4934g, resulting in a total percent yield of 86.74%. 1H NMR (400 MHz, DMSO) δ 9.47 (s, 1H), 5.52 (dtd, J = 14.0, 7.0, 1.8 Hz, 2H), 5.37 (dq, J = 13.3, 6.3 Hz, 2H), 3.84 (dq, J = 5.8, 2.7 Hz, 2H), 3.44 (dd, J = 6.1, 3.9 Hz, 2H), 3.14 (s, 9H), 2.80 (d, J = 7.0 Hz, 4H), 1.61 (dd, J = 6.4, 1.8 Hz, 6H).
[1] GALLOWAY J D. The Synthesis and Characterization of Ionic Liquids using Nitrogen-Based Cations for Transdermal Delivery[C]. 2022. | | Hazard | Choline bicarbonate can cause skin and eye irritation, as well as potential respiratory irritation. | | Biochem/physiol Actions | Acyl group acceptor |
| | Choline bicarbonate Preparation Products And Raw materials |
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